Gene Symbol | CMA1 |
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Entrez Gene | 1215 |
Alt Symbol | CYH, MCT1, chymase |
Species | Human |
Gene Type | protein-coding |
Description | chymase 1, mast cell |
Other Description | alpha-chymase|chymase|chymase 1 preproprotein transcript E|chymase 1 preproprotein transcript I|chymase, heart|chymase, mast cell|mast cell protease I |
Swissprots | Q9UDH5 Q3SY36 Q16018 Q3SY37 B5BUM8 P23946 |
Accessions | AAA52020 AAA52021 CAA41796 EAW66007 P23946 AB451464 BAG70278 BC069110 AAH69110 BC069370 AAH69370 BC069490 AAH69490 BC103974 AAI03975 BC103975 AAI03976 DQ082727 AAZ06432 DQ082729 AAZ06434 HY275608 M69136 AAA52019 S61334 AAB26828 XM_011536394 XP_011534696 NM_001308083 NP_001295012 NM_001836 NP_001827 |
Function | Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. |
Subcellular Location | Secreted. Cytoplasmic granule. Note=Mast cell granules. |
Tissue Specificity | Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions. {ECO:0000269|PubMed:8144971}. |
Top Pathways | Renin-angiotensin system |
CMA1 / MCT1 / Chymase Antibody Blocking Peptide - LS-E26850 from LifeSpan Bioscience
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MCTS1 Antibody Blocking Peptide - LS-E14931 from LifeSpan Bioscience
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MCTS1 Antibody Blocking Peptide - LS-E8361 from LifeSpan Bioscience
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MCTS1 Antibody Blocking Peptide - LS-E27993 from LifeSpan Bioscience
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CMA1-Antibody-C-term-Blocking-Peptide - BP7655b from Abgent, a WuXi AppTec company
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Recombinant Human Chymase/CMA1, CF - 4099-SE-010 from R&D Systems
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Human CMA1 protein (His Tag) - orb138581 from Biorbyt
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CMA1 Blocking Peptide - 33R-2795 from Fitzgerald
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Mast Cell Chymase Peptide - AC21-1683-P from Abcore
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CMA1 Peptide - 42-759P from ProSci
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CMA1 fusion protein - ag12909 from Proteintech Group
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CMA1 fusion protein - ag12921 from Proteintech Group
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Recombinant Human Chymase 1, Mast Cell - CMA1-722H from Creative Biomart
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Recombinant Human CMA1, His tagged - CMA1-2503H from Creative Biomart
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Recombinant Human CMA1, GST-tagged - CMA1-11359H from Creative Biomart
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Recombinant Chymase 1, Mast Cell (CMA1) - RPG515Hu01 from Uscn Life Science Inc.
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Recombinant Chymase 1, Mast Cell (CMA1) - RPG515Mu01 from Uscn Life Science Inc.
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Recombinant Chymase 1, Mast Cell (CMA1) - RPG515Ra01 from Uscn Life Science Inc.
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Human CMA1 / Chymase 1 Protein (His Tag) - 11482-H08B-10 from Sino Biological
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Recombinant Solute Carrier Family 16, Member 1 (SLC16A1) - RPE431Hu01 from Cloud-clone
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Recombinant Chymase 1, Mast Cell (CMA1) - RPG515Hu01 from Cloud-clone
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Recombinant Human Chymase(CMA1) - CSB-YP005599HU CSB-EP005599HU CSB-BP005599HU CSB-MP005599HU from Cusabio
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Recombinant Human Chymase/CMA1 Protein, CF - 4099-SE from R&D Systems
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CMA1 Protein - abx163703 from Abbexa
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CMA1, Peptide - MBS427416 from MyBioSource
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