Ier3

Gene Symbol Ier3
Entrez Gene 15937
Alt Symbol AI663993, IEX-1, cI-3, gly96
Species Mouse
Gene Type protein-coding
Description immediate early response 3
Other Description cAMP inducible gene 3|immediate early protein GLY96|immediate early response 3 protein|radiation-inducible immediate-early gene IEX-1
Swissprots P46694
Accessions AAO39405 EDL23233 EDL23234 P46694 AK003466 AK051003 BAC34493 AK170477 BAE41821 BC006950 AAH06950 CT010247 CAJ18455 CT010271 CAJ18479 X67644 NM_133662 NP_598423
Function May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A- PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival (By similarity). As a member of the NUPR1/RELB/IER3 survival pathway, may allow the development of pancreatic intraepithelial neoplasias. {ECO:0000250, ECO:0000269|PubMed:22565310}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Expressed predominantly in the lung, testes and the uterus.

IEX-1 CRISPR/Cas9 KO Plasmid (m) - sc-421028 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 HDR Plasmid (m) - sc-421028-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 Double Nickase Plasmid (m) - sc-421028-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 Double Nickase Plasmid (m2) - sc-421028-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 CRISPR Activation Plasmid (m) - sc-421028-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 CRISPR Activation Plasmid (m2) - sc-421028-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 Lentiviral Activation Particles (m) - sc-421028-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 Lentiviral Activation Particles (m2) - sc-421028-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

IEX-1 siRNA (m) - sc-146148 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IEX-1 shRNA Plasmid (m) - sc-146148-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

IEX-1 shRNA (m) Lentiviral Particles - sc-146148-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU038321 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN33614 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33614 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

shRNA set against Mouse IER3 (NM_133662.2) - SHH316701 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Ier3(NM_133662.2) - SHL165376 from Creative biogene

Category siRNA
Species Reactivities Mouse

IER3 miRNA 3'UTR clone - MiUTR1M-05885 from Creative biogene

Species Reactivities Mouse
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