GPX1

Gene Symbol GPX1
Entrez Gene 2876
Alt Symbol GPXD, GSHPX1
Species Human
Gene Type protein-coding
Description glutathione peroxidase 1
Other Description GPx-1|GSHPx-1|cellular glutathione peroxidase
Swissprots Q9BW12 E9PAS1 P07203 Q7Z5H1
Accessions AAA67540 AAB84255 AAP80181 CAB37833 EAW64976 EAW64977 P07203 AK130160 AK225835 BC000742 AAH00742 BC007865 AAH07865 BC070258 AAH70258 KJ534852 AHW56492 KJ534853 AHW56493 M21304 AAA75389 X13709 CAA31992 X13710 CAA31993 Y00433 CAA68491 NM_000581 NP_000572 NM_201397 NP_958799
Function Protects the hemoglobin in erythrocytes from oxidative breakdown.
Subcellular Location Cytoplasm.
Top Pathways Amyotrophic lateral sclerosis (ALS), Huntington's disease, Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism

GPX1 (C8C4) Rabbit mAb - 3286 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C8C4
Western blot analysis of extracts from 293 and THP-1 cells using GPX1 (C8C4) Rabbit mAb.

GPX1 Antibody - 3206 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293 and THP1 cells, using GPX1 Antibody.

GPx-1 (N-20) - sc-22145 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
GPx-1 (N-20): sc-22145. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing cytoplasmic staining of macrophages and pneumocytes.

GPx-1 (H-19) - sc-22146 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GPx-1/2 (B-6) - sc-133160 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GPx-1/2 (B-6): sc-133160. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic staining of cells in seminiferous ducts and Leydig cells.

GPx-1/2 (D-12) - sc-133152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GPx-1/2 (D-12): sc-133152. Western blot analysis of GPx-1/2 expression in SK-N-SH (A) and THP-1 (B) whole cell lysates and mouse liver (C) and rat liver (D) tissue extracts.

GPx-1/2 (H-151) - sc-30147 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GPx-1/2 (H-151): sc-30147. Western blot analysis of GPx-1/2 expression in THP-1 (A) whole cell lysate and rat liver (B) and mouse liver (C) tissue extracts. Note the presence of GPx multimers.

Anti-Glutathione Peroxidase 1 antibody - ab21966 from Abcam

Prices $384.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal
DAB staining of microglia with GPx1S in human brain tissue. Primary antibody (1/400) secondary antibody donkey anti-sheep - biotin (1/3000) followed by Vector ABC kit.

Anti-Glutathione Peroxidase 1 antibody - ab50427 from Abcam

Prices $384.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ab50427 (20µg/ml) staining of PFA-perfused cryosection of Porcin Kidney following microwave antigen retrieval with citrate buffer pH 3 and CY3-staining shows staining of cytoplasm in PCT epithelial cells.

Anti-Glutathione Peroxidase 1 antibody - ab113090 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab113090 at 10 &microg/ml staining Glutathione Peroxidase 1 in Formalin-fixed, Paraffin-embedded Human Breast tissue by Immunohistochemistry.

Anti-Glutathione Peroxidase 1 antibody - ab111077 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab111077, at 3.75µg/ml, staining GPX1 in formalin-fixed, paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.

Anti-Glutathione Peroxidase 1 antibody - ab134697 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Glutathione Peroxidase 1 antibody (ab134697) at 1/500 dilution + THP1 cell extract at 30 µg

Anti-Glutathione Peroxidase 1 antibody [2A10] - ab16735 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A10

Anti-Glutathione Peroxidase 1 antibody [42C9] - ab16736 from Abcam

Prices $372.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 42C9

Anti-Glutathione Peroxidase 1 antibody [EPR3311] - ab108429 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3311
All lanes : Anti-Glutathione Peroxidase 1 antibody [EPR3311] (ab108429) at 1/1000 dilutionLane 1 : Human fetal liver lysate Lane 2 : SH SY5Y cell lysateLane 3 : THP1 cell lysateLysates/proteins at 10 µg per lane.

Anti-Glutathione Peroxidase 1 antibody [EPR3312] - ab108427 from Abcam

Prices $397.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3312
Overlay histogram showing HepG2 cells stained with ab108427 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab108427, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HepG2 cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-Glutathione Peroxidase 1 antibody [EPR3312] (Alexa Fluor® 488) - ab197527 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3312
ab197527 staining Glutathione Peroxidase 1 in Hek293 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197527 at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Glutathione Peroxidase 1 antibody [EPR3312] (Alexa Fluor® 647) - ab197033 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3312
ab197033 staining Glutathione Peroxidase 1 in Hek293 cells. The cells were fixed with 100% methanol (5 min), permeabilized in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated with ab197033 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal [DM1A] to alpha Tubulin (Alexa Fluor® 488, shown in green) at 1/167 dilution, overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.This product also gave a positive signal under the same testing conditions in Hek293 cells fixed with 4% formaldehyde (10 min).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Glutathione Peroxidase 1 antibody [EPR3312] (HRP) - ab197034 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3312
Anti-Glutathione Peroxidase 1 antibody [EPR3312] (HRP) (ab197034) at 1/5000 dilution + THP1 (Human acute monocytic leukemia cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-GPX1 / Glutathione Peroxidase Antibody (aa116-146) - LS-C344054 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
GPX1 antibody IHC-paraffin: Human Intestinal Cancer Tissue.

Anti-GPX1 / Glutathione Peroxidase Antibody (aa48-201) - LS-C36466 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-GPX1 / Glutathione Peroxidase Antibody (AP) - LS-C41940 from LifeSpan Bioscience

Prices $360.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-GPX1 / Glutathione Peroxidase Antibody (aa175-194) - LS-C66684 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

Anti-GPX1 / Glutathione Peroxidase Antibody - LS-C129316 from LifeSpan Bioscience

Prices $455.00
Sizes 1 ml
Host Sheep
Clonality Polyclonal

Anti-GPX1 / Glutathione Peroxidase Antibody - LS-C129318 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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