Gene Symbol | GPX1 |
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Entrez Gene | 2876 |
Alt Symbol | GPXD, GSHPX1 |
Species | Human |
Gene Type | protein-coding |
Description | glutathione peroxidase 1 |
Other Description | GPx-1|GSHPx-1|cellular glutathione peroxidase |
Swissprots | Q9BW12 E9PAS1 P07203 Q7Z5H1 |
Accessions | AAA67540 AAB84255 AAP80181 CAB37833 EAW64976 EAW64977 P07203 AK130160 AK225835 BC000742 AAH00742 BC007865 AAH07865 BC070258 AAH70258 KJ534852 AHW56492 KJ534853 AHW56493 M21304 AAA75389 X13709 CAA31992 X13710 CAA31993 Y00433 CAA68491 NM_000581 NP_000572 NM_201397 NP_958799 |
Function | Protects the hemoglobin in erythrocytes from oxidative breakdown. |
Subcellular Location | Cytoplasm. |
Top Pathways | Amyotrophic lateral sclerosis (ALS), Huntington's disease, Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |
GPx-1 CRISPR/Cas9 KO Plasmid (h) - sc-400631 from Santa Cruz Biotechnology
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GPx-1 HDR Plasmid (h) - sc-400631-HDR from Santa Cruz Biotechnology
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GPx-1 Double Nickase Plasmid (h) - sc-400631-NIC from Santa Cruz Biotechnology
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GPx-1 Double Nickase Plasmid (h2) - sc-400631-NIC-2 from Santa Cruz Biotechnology
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GPx-1 CRISPR Activation Plasmid (h) - sc-400631-ACT from Santa Cruz Biotechnology
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GPx-1 CRISPR Activation Plasmid (h2) - sc-400631-ACT-2 from Santa Cruz Biotechnology
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GPx-1 Lentiviral Activation Particles (h) - sc-400631-LAC from Santa Cruz Biotechnology
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GPx-1 Lentiviral Activation Particles (h2) - sc-400631-LAC-2 from Santa Cruz Biotechnology
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GPx-1 siRNA (h) - sc-40646 from Santa Cruz Biotechnology
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GPx-1 shRNA Plasmid (h) - sc-40646-SH from Santa Cruz Biotechnology
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GPx-1 shRNA (h) Lentiviral Particles - sc-40646-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU218531 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9645 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9645 from Sigma-Aldrich
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GPX1 siRNA (Human) - CRH1933 from Cohesion Biosciences
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GPX1 - MBS8214033 from MyBioSource
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GPx-1 CRISPR/Cas9 KO Plasmid (h2) - sc-400631-KO-2 from Santa Cruz Biotechnology
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GPx-1 HDR Plasmid (h2) - sc-400631-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GPX1 (NM_000581.2) - SHH307362 from Creative biogene
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shRNA set against Human GPX1(NM_000581.2) - SHH102305 from Creative biogene
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shRNA set against Human GPX1(NM_201397.1) - SHH102341 from Creative biogene
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GPX1 shRNA Plasmid (Human) - CHH1933 from Cohesion Biosciences
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GPX1 miRNA 3'UTR clone - MiUTR1H-04244 from Creative biogene
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GPX1 miRNA 3'UTR clone - MiUTR1H-04245 from Creative biogene
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