CCDC78

Gene Symbol CCDC78
Entrez Gene 124093
Alt Symbol C16orf25, CNM4, JFP10, hsCCDC78
Species Human
Gene Type protein-coding
Description coiled-coil domain containing 78
Other Description coiled-coil domain-containing protein 78
Swissprots Q8NAY7 Q05BY7 Q6T2V5 B4E1U6 Q96S12 Q05CA0 Q8IUR3 B4DNY4 Q6ZR33 A2IDD5
Accessions A2IDD5 AAK61249 EAW85734 EAW85735 EAW85736 EAW85737 EAW85738 EAW85739 EAW85740 EAW85741 EAW85742 EAW85743 EAW85744 EAW85745 AK057178 AK091831 BAC03757 AK127495 BAC87006 AK128538 BAC87488 AK128575 AK298111 BAG60396 AK303991 BAG64908 AY439221 AAR13900 BC027941 BC042110 AAH42110 DC341680 XM_005255106 XP_005255163 XM_006720838 XP_006720901 XM_006720843 XP_006720906 XM_011522356 XP_011520658 XM_011522357 XP_011520659 XM_011522358 XP_011520660 XM_011522359 XP_011520661 XM_011522360 XP_011520662 XM_011522361 XP_011520663 XM_011522362 XP_011520664 XM_011522363 XP_011520665 XM_011522364 XP_011520666 XM_011522365 XP_011520667 XM_011522366 XP_011520668 XM_011522367 XP_011520669 XM_011522368 XP_011520670 XM_011522369 XP_011520671 XM_011522370 XP_011520672 XM_011522371 XP_011520673 NM_173476 NM_001031737 NP_001026907
Function Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome. {ECO:0000269|PubMed:24075808}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, perinuclear region. Cell membrane, sarcolemma. Sarcoplasmic reticulum. Note=Localizes to centrioles and deuterosome. Found primarily in the perinuclear region as well as along the sarcolemmal membrane and in reticular pattern within the sarcoplasm.
Tissue Specificity Expressed primarily in skeletal muscle. {ECO:0000269|PubMed:22818856}.

CCDC78 CRISPR/Cas9 KO Plasmid (h) - sc-414210 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 HDR Plasmid (h) - sc-414210-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 Double Nickase Plasmid (h) - sc-414210-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 Double Nickase Plasmid (h2) - sc-414210-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 CRISPR Activation Plasmid (h) - sc-414210-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 CRISPR Activation Plasmid (h2) - sc-414210-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 Lentiviral Activation Particles (h) - sc-414210-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 Lentiviral Activation Particles (h2) - sc-414210-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCDC78 siRNA (h) - sc-93201 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC78 shRNA Plasmid (h) - sc-93201-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCDC78 shRNA (h) Lentiviral Particles - sc-93201-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU098281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5565 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5565 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CCDC78 siRNA (Human) - CRJ4752 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CCDC78 - MBS8211188 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CCDC78 (NM_001031737.2) - SHH257105 from Creative biogene

Category siRNA
Species Reactivities Human

CCDC78 shRNA Plasmid (Human) - CHJ4752 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CCDC78 miRNA 3'UTR clone - MiUTR3H-13349 from Creative biogene

Species Reactivities Human
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