Gene Symbol | CCDC78 |
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Entrez Gene | 124093 |
Alt Symbol | C16orf25, CNM4, JFP10, hsCCDC78 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 78 |
Other Description | coiled-coil domain-containing protein 78 |
Swissprots | Q8NAY7 Q05BY7 Q6T2V5 B4E1U6 Q96S12 Q05CA0 Q8IUR3 B4DNY4 Q6ZR33 A2IDD5 |
Accessions | A2IDD5 AAK61249 EAW85734 EAW85735 EAW85736 EAW85737 EAW85738 EAW85739 EAW85740 EAW85741 EAW85742 EAW85743 EAW85744 EAW85745 AK057178 AK091831 BAC03757 AK127495 BAC87006 AK128538 BAC87488 AK128575 AK298111 BAG60396 AK303991 BAG64908 AY439221 AAR13900 BC027941 BC042110 AAH42110 DC341680 XM_005255106 XP_005255163 XM_006720838 XP_006720901 XM_006720843 XP_006720906 XM_011522356 XP_011520658 XM_011522357 XP_011520659 XM_011522358 XP_011520660 XM_011522359 XP_011520661 XM_011522360 XP_011520662 XM_011522361 XP_011520663 XM_011522362 XP_011520664 XM_011522363 XP_011520665 XM_011522364 XP_011520666 XM_011522365 XP_011520667 XM_011522366 XP_011520668 XM_011522367 XP_011520669 XM_011522368 XP_011520670 XM_011522369 XP_011520671 XM_011522370 XP_011520672 XM_011522371 XP_011520673 NM_173476 NM_001031737 NP_001026907 |
Function | Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase. Essential for centriole amplification and is required for CEP152 localization to the deuterosome. {ECO:0000269|PubMed:24075808}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, perinuclear region. Cell membrane, sarcolemma. Sarcoplasmic reticulum. Note=Localizes to centrioles and deuterosome. Found primarily in the perinuclear region as well as along the sarcolemmal membrane and in reticular pattern within the sarcoplasm. |
Tissue Specificity | Expressed primarily in skeletal muscle. {ECO:0000269|PubMed:22818856}. |
Anti-CCDC78 antibody - ab150871 from Abcam
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Anti-CCDC78 Antibody (aa127-165) - LS-C82723 from LifeSpan Bioscience
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CCDC78 Antibody - NBP2-14455 from Novus Biologicals
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CCDC78 Antibody - NBP1-88441 from Novus Biologicals
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CCDC78 Antibody - NBP1-55424 from Novus Biologicals
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Anti-CCDC78 antibody produced in rabbit - HPA041384 from Sigma-Aldrich
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CCDC78 antibody - middle region (ARP53233_P050) - ARP53233_P050 from Aviva Systems Biology
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CCDC78 antibody, Internal - GTX45581 from GeneTex
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CCDC78 antibody - 70R-3751 from Fitzgerald
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CCDC78 antibody - H00124093-B01P from Acris Antibodies
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CCDC78 Antibody - 30-850 from ProSci
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CCDC78 Antibody - GWB-MS984C from Genway Biotech
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Anti-CCDC78 (aa 238-341) polyclonal antibody - DPABH-03018 from Creative Diagnostics
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CCDC78, Polyclonal Antibody - MBS5301796 from MyBioSource
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Anti-CCDC78 antibody produced in rabbit - HPA041186 from Sigma-Aldrich
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CCDC78 antibody - TA337790 from Acris Antibodies
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Anti-CCDC78 Antibody A12661 - A12661 from Boster Bio
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CCDC78 antibody - middle region : Biotin (ARP53233_P050-Biotin) - ARP53233_P050-Biotin from Aviva Systems Biology
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CCDC78 antibody - middle region : FITC (ARP53233_P050-FITC) - ARP53233_P050-FITC from Aviva Systems Biology
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CCDC78 antibody - middle region : HRP (ARP53233_P050-HRP) - ARP53233_P050-HRP from Aviva Systems Biology
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CCDC78 antibody - C-terminal region (OAAB00339) - OAAB00339 from Aviva Systems Biology
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Anti-CCDC78 Antibody (aa127-165, HRP) - LS-C457277 from LifeSpan Bioscience
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Anti-CCDC78 Antibody (aa127-165, Biotin) - LS-C457275 from LifeSpan Bioscience
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Anti-CCDC78 Antibody (aa127-165, FITC) - LS-C457276 from LifeSpan Bioscience
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