Gene Symbol |
CCR9
|
Entrez Gene |
10803
|
Alt Symbol |
CC-CKR-9, CDw199, GPR-9-6, GPR28
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-C motif) receptor 9
|
Other Description |
C-C chemokine receptor type 9|G protein-coupled receptor 28
|
Swissprots |
P51686 Q4VBM3 Q9UQQ6 Q549E0
|
Accessions |
AAA93319 AAO92294 EAW64751 EAW64752 P51686 AF145207 AAD38539 AF145439 AAF66699 AF145440 AAF66700 AJ132337 CAB43477 AK312824 BAG35681 AK313366 BAG36166 BC069678 AAH69678 BC095516 AAH95516 DB103756 DB132476 XM_011533312 XP_011531614 NM_001256369 NP_001243298 NM_006641 NP_006632 NM_031200 NP_112477
|
Function |
Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Highly expressed in the thymus and low in lymph nodes and spleen. {ECO:0000269|PubMed:10229797, ECO:0000269|PubMed:10640743}.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Chemokine signaling pathway
|