Gene Symbol | CCR9 |
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Entrez Gene | 10803 |
Alt Symbol | CC-CKR-9, CDw199, GPR-9-6, GPR28 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 9 |
Other Description | C-C chemokine receptor type 9|G protein-coupled receptor 28 |
Swissprots | P51686 Q4VBM3 Q9UQQ6 Q549E0 |
Accessions | AAA93319 AAO92294 EAW64751 EAW64752 P51686 AF145207 AAD38539 AF145439 AAF66699 AF145440 AAF66700 AJ132337 CAB43477 AK312824 BAG35681 AK313366 BAG36166 BC069678 AAH69678 BC095516 AAH95516 DB103756 DB132476 XM_011533312 XP_011531614 NM_001256369 NP_001243298 NM_006641 NP_006632 NM_031200 NP_112477 |
Function | Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in the thymus and low in lymph nodes and spleen. {ECO:0000269|PubMed:10229797, ECO:0000269|PubMed:10640743}. |
Top Pathways | Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Chemokine signaling pathway |
CKR-9 CRISPR/Cas9 KO Plasmid (h) - sc-406848 from Santa Cruz Biotechnology
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CKR-9 HDR Plasmid (h) - sc-406848-HDR from Santa Cruz Biotechnology
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CKR-9 Double Nickase Plasmid (h) - sc-406848-NIC from Santa Cruz Biotechnology
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CKR-9 Double Nickase Plasmid (h2) - sc-406848-NIC-2 from Santa Cruz Biotechnology
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CKR-9 CRISPR Activation Plasmid (h) - sc-406848-ACT from Santa Cruz Biotechnology
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CKR-9 CRISPR Activation Plasmid (h2) - sc-406848-ACT-2 from Santa Cruz Biotechnology
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CKR-9 Lentiviral Activation Particles (h) - sc-406848-LAC from Santa Cruz Biotechnology
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CKR-9 Lentiviral Activation Particles (h2) - sc-406848-LAC-2 from Santa Cruz Biotechnology
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CKR-9 siRNA (h) - sc-39892 from Santa Cruz Biotechnology
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CKR-9 shRNA Plasmid (h) - sc-39892-SH from Santa Cruz Biotechnology
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CKR-9 shRNA (h) Lentiviral Particles - sc-39892-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU061111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5660 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5660 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08546 from Sigma-Aldrich
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CCR9 siRNA (Human) - CRH7363 from Cohesion Biosciences
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CCR9 - MBS8237527 from MyBioSource
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shRNA set against Human CCR9 (NM_006641.3) - SHH258229 from Creative biogene
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CCR9 shRNA Plasmid (Human) - CHH7363 from Cohesion Biosciences
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