| Gene Symbol |
MTO1
|
| Entrez Gene |
25821
|
| Alt Symbol |
CGI-02, COXPD10
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mitochondrial tRNA translation optimization 1
|
| Other Description |
homolog of yeast Mto1|mitochondrial MTO1-3|mitochondrial translation optimization 1 homolog|protein MTO1 homolog, mitochondrial
|
| Swissprots |
Q8WZ57 Q96FE6 Q9Y2Z2 Q5SWL4 Q5SWL2 Q9BS06 Q8NDN7 Q5SWL3 B3KQB5
|
| Accessions |
AAL35894 CAF86693 EAW48760 EAW48761 EAW48762 EAW48763 EAW48764 EAW48765 EAW48766 EAW48767 EAW48768 Q9Y2Z2 AF132937 AAD27712 AF319422 AAG42814 AF469110 AAL82394 AF469111 AAL82395 AJ420530 AK026073 AK074625 BAG51977 AK225828 AL833823 CAD38685 AY078985 AAL85490 AY078986 AAL85491 AY947715 AAY51627 AY947716 AAY51628 BC005808 AAH05808 BC011051 AAH11051 BE501391 DN993156 XM_006715444 XP_006715507 XM_006715445 XP_006715508 XM_006715446 XP_006715509 XM_006715447 XP_006715510 XM_011535723 XP_011534025 XM_011535724 XP_011534026 XM_011535725 XP_011534027 NM_001123226 NP_001116698 NM_012123 NP_036255 NM_133645 NP_598400
|
| Function |
Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. {ECO:0000269|PubMed:12011058}.
|
| Subcellular Location |
Mitochondrion {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea. {ECO:0000269|PubMed:12011058}.
|