MTO1

Gene Symbol MTO1
Entrez Gene 25821
Alt Symbol CGI-02, COXPD10
Species Human
Gene Type protein-coding
Description mitochondrial tRNA translation optimization 1
Other Description homolog of yeast Mto1|mitochondrial MTO1-3|mitochondrial translation optimization 1 homolog|protein MTO1 homolog, mitochondrial
Swissprots Q8WZ57 Q96FE6 Q9Y2Z2 Q5SWL4 Q5SWL2 Q9BS06 Q8NDN7 Q5SWL3 B3KQB5
Accessions AAL35894 CAF86693 EAW48760 EAW48761 EAW48762 EAW48763 EAW48764 EAW48765 EAW48766 EAW48767 EAW48768 Q9Y2Z2 AF132937 AAD27712 AF319422 AAG42814 AF469110 AAL82394 AF469111 AAL82395 AJ420530 AK026073 AK074625 BAG51977 AK225828 AL833823 CAD38685 AY078985 AAL85490 AY078986 AAL85491 AY947715 AAY51627 AY947716 AAY51628 BC005808 AAH05808 BC011051 AAH11051 BE501391 DN993156 XM_006715444 XP_006715507 XM_006715445 XP_006715508 XM_006715446 XP_006715509 XM_006715447 XP_006715510 XM_011535723 XP_011534025 XM_011535724 XP_011534026 XM_011535725 XP_011534027 NM_001123226 NP_001116698 NM_012123 NP_036255 NM_133645 NP_598400
Function Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. {ECO:0000269|PubMed:12011058}.
Subcellular Location Mitochondrion {ECO:0000250}.
Tissue Specificity Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues of high metabolic rates including cochlea. {ECO:0000269|PubMed:12011058}.

MTO1 (D-12) - sc-161114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MTO1 (D-12): sc-161114. Western blot analysis of MTO1 expression in mouse liver tissue extract.

MTO1 (A-8) - sc-398760 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MTO1 (A-8): sc-398760. Western blot analysis of MTO1 expression in HeLa (A), MIA PaCa-2 (B), PC-3 (C) and RT-4 (D) whole cell lysates and human liver tissue extract (E).

MTO1 (E-16) - sc-161115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MTO1 (E-16): sc-161115. Western blot analysis of MTO1 expression in non-transfected: sc-117752 (A) and human MTO1 transfected: sc-111063 (B) 293T whole cell lysates.

MTO1 (H-290) - sc-382204 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MTO1 (H-5) - sc-398386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MTO1 (H-5): sc-398386. Western blot analysis of MTO1 expression in non-transfected 293T: sc-117752 (A), human MTO1 transfected 293T: sc-111063 (B), MIA PaCa-2 (C), PC-3 (D) and RT-4 (E) whole cell lysates.

Anti-MTO1 antibody - ab105066 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MTO1 antibody (ab105066) at 1 µg/ml + Human fetal muscle lysate at 10 µg

Anti-MTO1 antibody - ab78013 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human brain cortex tissue using 20µg/ml ab78013.

Anti-MTO1 antibody - ab58667 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MTO1 Antibody (aa182-231) - LS-C82858 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-MTO1 Antibody (C-Terminus) IHC-plus™ - LS-B1830 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MTO1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1830 concentration 20 ug/ml.

MTO1 Antibody - NBP1-54767 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MTO1 Antibody [NBP1-54767] - Detection of MTO1 in HeLa whole cell lysate enriched for mitochondria via digitonin treatment prior to cell pelleting (Hm lane) and human fibroblast whole cell lysate (Fi lane). Image provided by Maria Holmstrom of Gothenburg University.

MTO1 Antibody - NBP1-85932 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MTO1 Antibody - NBP1-85933 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MTO1 Antibody [NBP1-85933] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp

Anti-MTO1 antibody produced in rabbit - HPA030232 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MTO1: <B>Cat. No. HPA030232</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in renal tubules.

Anti-MTO1 antibody produced in rabbit - HPA030230 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MTO1: <B>Cat. No. HPA030230</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in renal tubules.

MTO1 antibody - N-terminal region (ARP54841_P050) - ARP54841_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MTO1 antibody - GTX123372 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-MTO1 antibody used in ICC/IF. GTX123372

MTO1 antibody - GTX85750 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-MTO1 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX85750

MTO1 antibody, N-term - GTX45372 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

MTO1 antibody - 70R-18673 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

MTO1 Antibody (OALA02186) - OALA02186 from Aviva Systems Biology

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

MTO1 antibody - 70R-2514 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Mto1 Antibody - abx113822 from Abbexa

Host Rabbit
Clonality Polyclonal

MTO1 antibody - 15650-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human  liver were subjected to SDS PAGE followed by western blot with 15650-1-AP(MTO1 Antibody) at dilution of 1:1200

MTO1 (C-term) antibody - AP08312PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Brain, cortex: Formalin-Fixed Paraffin Embedded (FFPE)
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