Gene Symbol |
AUH
|
Entrez Gene |
549
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
AU RNA binding protein/enoyl-CoA hydratase
|
Other Description |
3-methylglutaconyl-CoA hydratase|AU RNA-binding protein/enoyl-Coenzyme A hydratase|AU-binding protein/Enoyl-CoA hydratase|AU-specific RNA-binding enoyl-CoA hydratase|methylglutaconyl-CoA hydratase, mitochondrial
|
Swissprots |
Q8WUE4 B1ALV7 B1ALV8 Q13825
|
Accessions |
EAW62794 EAW62795 Q13825 AK124142 AK302453 BAG63748 AM393420 CAL38298 AV751432 BC020722 AAH20722 BG706374 BI667104 DA724873 DQ892036 ABM82962 DQ895227 ABM86153 X79888 CAA56260 XM_005252066 XP_005252123 XM_005252067 XP_005252124 XM_005252068 XP_005252125 XM_005252069 XP_005252126 XM_005252072 XP_005252129 XM_005252073 XP_005252130 XM_006717150 XP_006717213 XM_011518800 XP_011517102 XM_011518801 XP_011517103 XM_011518802 XP_011517104 XM_011518803 XP_011517105 XM_011518804 XP_011517106 XR_929814 NM_001306190 NP_001293119 NM_001698 NP_001689
|
Function |
Catalyzes the conversion of 3-methylglutaconyl-CoA to 3- hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs. {ECO:0000269|PubMed:11738050, ECO:0000269|PubMed:12434311, ECO:0000269|PubMed:12655555, ECO:0000269|PubMed:7892223}.
|
Subcellular Location |
Mitochondrion {ECO:0000250}.
|
Top Pathways |
Valine, leucine and isoleucine degradation
|