| Gene Symbol |
CD1C
|
| Entrez Gene |
911
|
| Alt Symbol |
BDCA1, CD1, CD1A, R7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD1c molecule
|
| Other Description |
CD1C antigen, c polypeptide|T-cell surface glycoprotein CD1c|cortical thymocyte antigen CD1C|differentiation antigen CD1-alpha-3
|
| Swissprots |
P29017 Q5TDJ7 Q9UMM0 Q9UN96 Q6IAS4
|
| Accessions |
AAA51938 AAA51942 AAD37580 EAW52842 P29017 AA824381 AK226024 AK298234 BAG60503 AK310577 AK310710 BC126465 AAI26466 BC126467 AAI26468 CR457080 CAG33361 HQ258200 ADR82954 HQ258607 ADR83360 M28827 AAA51941 X79310 X79311 XM_005245579 XP_005245636 NM_001765 NP_001756
|
| Function |
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10786796, ECO:0000269|PubMed:10890914, ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:21167756}.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes.
|
| Tissue Specificity |
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
|
| Top Pathways |
Hematopoietic cell lineage
|
![Western Blot: CD1c Overexpression Lysate (Adult Normal) [NBP2-08178] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CD1c.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14637_CD1c%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08178-img0001.jpg)