Gene Symbol | CD1C |
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Entrez Gene | 911 |
Alt Symbol | BDCA1, CD1, CD1A, R7 |
Species | Human |
Gene Type | protein-coding |
Description | CD1c molecule |
Other Description | CD1C antigen, c polypeptide|T-cell surface glycoprotein CD1c|cortical thymocyte antigen CD1C|differentiation antigen CD1-alpha-3 |
Swissprots | P29017 Q5TDJ7 Q9UMM0 Q9UN96 Q6IAS4 |
Accessions | AAA51938 AAA51942 AAD37580 EAW52842 P29017 AA824381 AK226024 AK298234 BAG60503 AK310577 AK310710 BC126465 AAI26466 BC126467 AAI26468 CR457080 CAG33361 HQ258200 ADR82954 HQ258607 ADR83360 M28827 AAA51941 X79310 X79311 XM_005245579 XP_005245636 NM_001765 NP_001756 |
Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10786796, ECO:0000269|PubMed:10890914, ECO:0000269|PubMed:10899914, ECO:0000269|PubMed:21167756}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes. |
Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
Top Pathways | Hematopoietic cell lineage |
CD1C CRISPR/Cas9 KO Plasmid (h) - sc-403813 from Santa Cruz Biotechnology
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CD1C HDR Plasmid (h) - sc-403813-HDR from Santa Cruz Biotechnology
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CD1C Double Nickase Plasmid (h) - sc-403813-NIC from Santa Cruz Biotechnology
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CD1C Double Nickase Plasmid (h2) - sc-403813-NIC-2 from Santa Cruz Biotechnology
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CD1C CRISPR Activation Plasmid (h) - sc-403813-ACT from Santa Cruz Biotechnology
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CD1C CRISPR Activation Plasmid (h2) - sc-403813-ACT-2 from Santa Cruz Biotechnology
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CD1C Lentiviral Activation Particles (h) - sc-403813-LAC from Santa Cruz Biotechnology
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CD1C Lentiviral Activation Particles (h2) - sc-403813-LAC-2 from Santa Cruz Biotechnology
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CD1C siRNA (h) - sc-42746 from Santa Cruz Biotechnology
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CD1C shRNA Plasmid (h) - sc-42746-SH from Santa Cruz Biotechnology
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CD1C shRNA (h) Lentiviral Particles - sc-42746-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5691 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08835 from Sigma-Aldrich
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CD1C siRNA (Human) - CRH0640 from Cohesion Biosciences
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CD1c/BDCA-1 RNAi - H00000911-R01 from Novus Biologicals
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CD1C - MBS8224762 from MyBioSource
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shRNA set against Human CD1c (NM_001765.2) - SHH258589 from Creative biogene
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CD1C shRNA Plasmid (Human) - CHH0640 from Cohesion Biosciences
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CD1C miRNA 3'UTR clone - MiUTR1H-01846 from Creative biogene
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