| Gene Symbol | CCR6 |
|---|---|
| Entrez Gene | 1235 |
| Alt Symbol | BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-C motif) receptor 6 |
| Other Description | C-C chemokine receptor type 6|G protein-coupled receptor 29|G-protein coupled receptor 29|LARC receptor|chemokine (C-C) receptor 6|chemokine receptor-like 3|seven-transmembrane receptor, lymphocyte, 22 |
| Swissprots | E1P5C6 P78553 P51684 Q92846 |
| Accessions | AAB62714 AAC51125 CAB02144 EAW47506 EAW47507 P51684 AK223494 BAD97214 AK293015 BAF85704 AY242126 AAO92293 BC037960 AAH37960 CD692892 CD707633 DA645096 DN996219 DQ892462 ABM83388 DQ895674 ABM86600 U60000 AAB06949 U68030 AAC51124 U68031 AAD14874 NM_004367 NP_004358 NM_031409 NP_113597 |
| Function | Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. {ECO:0000269|PubMed:9169459}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes. |
| Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |