CCR6
| Gene Symbol | CCR6 |
|---|---|
| Entrez Gene | 1235 |
| Alt Symbol | BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-C motif) receptor 6 |
| Other Description | C-C chemokine receptor type 6|G protein-coupled receptor 29|G-protein coupled receptor 29|LARC receptor|chemokine (C-C) receptor 6|chemokine receptor-like 3|seven-transmembrane receptor, lymphocyte, 22 |
| Swissprots | E1P5C6 P78553 P51684 Q92846 |
| Accessions | AAB62714 AAC51125 CAB02144 EAW47506 EAW47507 P51684 AK223494 BAD97214 AK293015 BAF85704 AY242126 AAO92293 BC037960 AAH37960 CD692892 CD707633 DA645096 DN996219 DQ892462 ABM83388 DQ895674 ABM86600 U60000 AAB06949 U68030 AAC51124 U68031 AAD14874 NM_004367 NP_004358 NM_031409 NP_113597 |
| Function | Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. {ECO:0000269|PubMed:9169459}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes. |
| Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CKR-6 CRISPR/Cas9 KO Plasmid (h) - sc-403675 from Santa Cruz Biotechnology
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CKR-6 HDR Plasmid (h) - sc-403675-HDR from Santa Cruz Biotechnology
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CKR-6 Double Nickase Plasmid (h) - sc-403675-NIC from Santa Cruz Biotechnology
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CKR-6 Double Nickase Plasmid (h2) - sc-403675-NIC-2 from Santa Cruz Biotechnology
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CKR-6 CRISPR Activation Plasmid (h) - sc-403675-ACT from Santa Cruz Biotechnology
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CKR-6 CRISPR Activation Plasmid (h2) - sc-403675-ACT-2 from Santa Cruz Biotechnology
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CKR-6 Lentiviral Activation Particles (h) - sc-403675-LAC from Santa Cruz Biotechnology
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CKR-6 Lentiviral Activation Particles (h2) - sc-403675-LAC-2 from Santa Cruz Biotechnology
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CKR-6 siRNA (h) - sc-35064 from Santa Cruz Biotechnology
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CKR-6 shRNA Plasmid (h) - sc-35064-SH from Santa Cruz Biotechnology
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CKR-6 shRNA (h) Lentiviral Particles - sc-35064-V from Santa Cruz Biotechnology
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CCR6 RNAi - H00001235-R03 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5657 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5657 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10509 from Sigma-Aldrich
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CCR6 siRNA (Human) - CRH0871 from Cohesion Biosciences
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CCR6 RNAi - H00001235-R04 from Novus Biologicals
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CCR6 - MBS8206274 from MyBioSource
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shRNA set against Human CCR6 (NM_004367.5) - SHH258193 from Creative biogene
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shRNA set against Human CCR6(NM_004367.5) - SHG153577 from Creative biogene
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Human CCR6 siRNA - orb261373 from Biorbyt
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CCR6 shRNA Plasmid (Human) - CHH0871 from Cohesion Biosciences
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CCR6 miRNA 3'UTR clone - MiUTR1H-01828 from Creative biogene
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CCR6 miRNA 3'UTR clone - MiUTR3H-04442 from Creative biogene
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