Gene Symbol |
CCR6
|
Entrez Gene |
1235
|
Alt Symbol |
BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-C motif) receptor 6
|
Other Description |
C-C chemokine receptor type 6|G protein-coupled receptor 29|G-protein coupled receptor 29|LARC receptor|chemokine (C-C) receptor 6|chemokine receptor-like 3|seven-transmembrane receptor, lymphocyte, 22
|
Swissprots |
E1P5C6 P78553 P51684 Q92846
|
Accessions |
AAB62714 AAC51125 CAB02144 EAW47506 EAW47507 P51684 AK223494 BAD97214 AK293015 BAF85704 AY242126 AAO92293 BC037960 AAH37960 CD692892 CD707633 DA645096 DN996219 DQ892462 ABM83388 DQ895674 ABM86600 U60000 AAB06949 U68030 AAC51124 U68031 AAD14874 NM_004367 NP_004358 NM_031409 NP_113597
|
Function |
Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. {ECO:0000269|PubMed:9169459}.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|