| Gene Symbol |
RFX1
|
| Entrez Gene |
5989
|
| Alt Symbol |
EFC, RFX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulatory factor X, 1 (influences HLA class II expression)
|
| Other Description |
MHC class II regulatory factor RFX|MHC class II regulatory factor RFX1|enhancer factor C|regulatory factor X 1|trans-acting regulatory factor 1|transcription factor RFX1
|
| Swissprots |
P22670
|
| Accessions |
EAW84387 P22670 A20498 CAA01506 AI917511 AK309824 BC049826 AAH49826 BM557928 BM662273 X58964 CAA41730 XM_011528165 XP_011526467 XM_011528166 XP_011526468 XM_011528167 XP_011526469 XM_011528168 XP_011526470 XM_011528169 XP_011526471 XM_011528170 XP_011526472 NM_002918 NP_002909
|
| Function |
Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter.
|
| Subcellular Location |
Nucleus.
|