Gene Symbol | RFX1 |
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Entrez Gene | 5989 |
Alt Symbol | EFC, RFX |
Species | Human |
Gene Type | protein-coding |
Description | regulatory factor X, 1 (influences HLA class II expression) |
Other Description | MHC class II regulatory factor RFX|MHC class II regulatory factor RFX1|enhancer factor C|regulatory factor X 1|trans-acting regulatory factor 1|transcription factor RFX1 |
Swissprots | P22670 |
Accessions | EAW84387 P22670 A20498 CAA01506 AI917511 AK309824 BC049826 AAH49826 BM557928 BM662273 X58964 CAA41730 XM_011528165 XP_011526467 XM_011528166 XP_011526468 XM_011528167 XP_011526469 XM_011528168 XP_011526470 XM_011528169 XP_011526471 XM_011528170 XP_011526472 NM_002918 NP_002909 |
Function | Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. |
Subcellular Location | Nucleus. |
RFX1 CRISPR/Cas9 KO Plasmid (h) - sc-403144 from Santa Cruz Biotechnology
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RFX1 HDR Plasmid (h) - sc-403144-HDR from Santa Cruz Biotechnology
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RFX1 Double Nickase Plasmid (h) - sc-403144-NIC from Santa Cruz Biotechnology
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RFX1 Double Nickase Plasmid (h2) - sc-403144-NIC-2 from Santa Cruz Biotechnology
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RFX1 CRISPR Activation Plasmid (h) - sc-403144-ACT from Santa Cruz Biotechnology
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RFX1 CRISPR Activation Plasmid (h2) - sc-403144-ACT-2 from Santa Cruz Biotechnology
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RFX1 Lentiviral Activation Particles (h) - sc-403144-LAC from Santa Cruz Biotechnology
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RFX1 Lentiviral Activation Particles (h2) - sc-403144-LAC-2 from Santa Cruz Biotechnology
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RFX1 siRNA (h) - sc-37741 from Santa Cruz Biotechnology
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RFX1 shRNA Plasmid (h) - sc-37741-SH from Santa Cruz Biotechnology
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RFX1 shRNA (h) Lentiviral Particles - sc-37741-V from Santa Cruz Biotechnology
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RFX1 RNAi - H00005989-R01 from Novus Biologicals
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MISSION® esiRNA - EHU145291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18184 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18184 from Sigma-Aldrich
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RFX1 siRNA (Human) - CRH4057 from Cohesion Biosciences
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RFX1 - MBS8230412 from MyBioSource
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shRNA set against Human RFX1 (NM_002918.4) - SHH392388 from Creative biogene
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RFX1 shRNA Plasmid (Human) - CHH4057 from Cohesion Biosciences
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RFX1 miRNA 3'UTR clone - MiUTR3H-03066 from Creative biogene
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