Gene Symbol | SRM |
---|---|
Entrez Gene | 6723 |
Alt Symbol | PAPT, SPDSY, SPS1, SRML1 |
Species | Human |
Gene Type | protein-coding |
Description | spermidine synthase |
Other Description | putrescine aminopropyltransferase|spermidine synthase-1 |
Swissprots | Q15511 B1AKP9 P19623 |
Accessions | AAA60574 EAW71675 EAW71676 P19623 BC000309 AAH00309 BC033106 AAH33106 EU831469 ACE87156 EU831556 ACE86475 M34338 AAA36633 NM_003132 NP_003123 |
Function | Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. {ECO:0000269|PubMed:17585781}. |
Top Pathways | Cysteine and methionine metabolism, Arginine and proline metabolism, Glutathione metabolism, beta-Alanine metabolism |