Gene Symbol | SRM |
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Entrez Gene | 6723 |
Alt Symbol | PAPT, SPDSY, SPS1, SRML1 |
Species | Human |
Gene Type | protein-coding |
Description | spermidine synthase |
Other Description | putrescine aminopropyltransferase|spermidine synthase-1 |
Swissprots | Q15511 B1AKP9 P19623 |
Accessions | AAA60574 EAW71675 EAW71676 P19623 BC000309 AAH00309 BC033106 AAH33106 EU831469 ACE87156 EU831556 ACE86475 M34338 AAA36633 NM_003132 NP_003123 |
Function | Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. {ECO:0000269|PubMed:17585781}. |
Top Pathways | Cysteine and methionine metabolism, Arginine and proline metabolism, Glutathione metabolism, beta-Alanine metabolism |
SPDSY CRISPR/Cas9 KO Plasmid (h) - sc-411019 from Santa Cruz Biotechnology
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SPDSY HDR Plasmid (h) - sc-411019-HDR from Santa Cruz Biotechnology
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SPDSY Double Nickase Plasmid (h) - sc-411019-NIC from Santa Cruz Biotechnology
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SPDSY Double Nickase Plasmid (h2) - sc-411019-NIC-2 from Santa Cruz Biotechnology
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SPDSY CRISPR Activation Plasmid (h) - sc-411019-ACT from Santa Cruz Biotechnology
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SPDSY CRISPR Activation Plasmid (h2) - sc-411019-ACT-2 from Santa Cruz Biotechnology
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SPDSY Lentiviral Activation Particles (h) - sc-411019-LAC from Santa Cruz Biotechnology
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SPDSY Lentiviral Activation Particles (h2) - sc-411019-LAC-2 from Santa Cruz Biotechnology
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SPDSY siRNA (h) - sc-88193 from Santa Cruz Biotechnology
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SPDSY shRNA Plasmid (h) - sc-88193-SH from Santa Cruz Biotechnology
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SPDSY shRNA (h) Lentiviral Particles - sc-88193-V from Santa Cruz Biotechnology
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SRM RNAi - H00006723-R01 from Novus Biologicals
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MISSION® esiRNA - EHU052281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20576 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20576 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01598 from Sigma-Aldrich
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SRM siRNA (Human) - CRH4591 from Cohesion Biosciences
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SRM - MBS8237921 from MyBioSource
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shRNA set against Human Srm (NM_003132.2) - SHH417872 from Creative biogene
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shRNA set against Human SRM(NM_003132.2) - SHL035172 from Creative biogene
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Human SRM siRNA - orb265093 from Biorbyt
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SRM shRNA Plasmid (Human) - CHH4591 from Cohesion Biosciences
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SRM miRNA 3'UTR clone - MiUTR1H-09907 from Creative biogene
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