Gene Symbol |
SLC6A1
|
Entrez Gene |
6529
|
Alt Symbol |
GABATHG, GABATR, GAT1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
solute carrier family 6 (neurotransmitter transporter), member 1
|
Other Description |
GABA transporter 1|GAT-1|sodium- and chloride-dependent GABA transporter 1|solute carrier family 6 (neurotransmitter transporter, GABA), member 1|solute carrier family 6 member 1
|
Swissprots |
Q8N4K8 P30531
|
Accessions |
EAW64088 EAW64089 EAW64090 P30531 AK090958 AK295702 BAH12161 BC033904 AAH33904 BC057291 DA162953 DQ891222 ABM82148 DQ894405 ABM85331 X54673 CAA38484 XM_005265410 XP_005265467 XM_005265411 XP_005265468 XM_006713306 XP_006713369 XM_011534025 XP_011532327 XM_011534026 XP_011532328 XM_011534027 XP_011532329 XM_011534028 XP_011532330 NM_003042 NP_003033
|
Function |
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity). {ECO:0000250}.
|
Top Pathways |
GABAergic synapse
|