Gene Symbol | SLC6A1 |
---|---|
Entrez Gene | 6529 |
Alt Symbol | GABATHG, GABATR, GAT1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 1 |
Other Description | GABA transporter 1|GAT-1|sodium- and chloride-dependent GABA transporter 1|solute carrier family 6 (neurotransmitter transporter, GABA), member 1|solute carrier family 6 member 1 |
Swissprots | Q8N4K8 P30531 |
Accessions | EAW64088 EAW64089 EAW64090 P30531 AK090958 AK295702 BAH12161 BC033904 AAH33904 BC057291 DA162953 DQ891222 ABM82148 DQ894405 ABM85331 X54673 CAA38484 XM_005265410 XP_005265467 XM_005265411 XP_005265468 XM_006713306 XP_006713369 XM_011534025 XP_011532327 XM_011534026 XP_011532328 XM_011534027 XP_011532329 XM_011534028 XP_011532330 NM_003042 NP_003033 |
Function | Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity). {ECO:0000250}. |
Top Pathways | GABAergic synapse |
GABA T-1 CRISPR/Cas9 KO Plasmid (h) - sc-411007 from Santa Cruz Biotechnology
|
||||||||
GABA T-1 HDR Plasmid (h) - sc-411007-HDR from Santa Cruz Biotechnology
|
||||||||
GABA T-1 Double Nickase Plasmid (h) - sc-411007-NIC from Santa Cruz Biotechnology
|
||||||||
GABA T-1 Double Nickase Plasmid (h2) - sc-411007-NIC-2 from Santa Cruz Biotechnology
|
||||||||
GABA T-1 CRISPR Activation Plasmid (h) - sc-411007-ACT from Santa Cruz Biotechnology
|
||||||||
GABA T-1 CRISPR Activation Plasmid (h2) - sc-411007-ACT-2 from Santa Cruz Biotechnology
|
||||||||
GABA T-1 Lentiviral Activation Particles (h) - sc-411007-LAC from Santa Cruz Biotechnology
|
||||||||
GABA T-1 Lentiviral Activation Particles (h2) - sc-411007-LAC-2 from Santa Cruz Biotechnology
|
||||||||
GABA T-1 siRNA (h) - sc-44958 from Santa Cruz Biotechnology
|
||||||||
GABA T-1 shRNA Plasmid (h) - sc-44958-SH from Santa Cruz Biotechnology
|
||||||||
GABA T-1 shRNA (h) Lentiviral Particles - sc-44958-V from Santa Cruz Biotechnology
|
||||||||
GAT-1/SLC6A1 RNAi - H00006529-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU153901 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19670 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19670 from Sigma-Aldrich
|
||||||||
SLC6A1 siRNA (Human) - CRH4423 from Cohesion Biosciences
|
||||||||
SLC6A1 - MBS8205146 from MyBioSource
|
||||||||
shRNA set against Human Slc6a1 (NM_003042.3) - SHH411796 from Creative biogene
|
||||||||
Human SLC6A1 siRNA - orb264925 from Biorbyt
|
||||||||
SLC6A1 shRNA Plasmid (Human) - CHH4423 from Cohesion Biosciences
|
||||||||
SLC6A1 miRNA 3'UTR clone - MiUTR4H-TG08125 from Creative biogene
|