Gene Symbol | SHMT1 |
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Entrez Gene | 6470 |
Alt Symbol | CSHMT, SHMT |
Species | Human |
Gene Type | protein-coding |
Description | serine hydroxymethyltransferase 1 (soluble) |
Other Description | cytoplasmic serine hydroxymethyltransferase|glycine hydroxymethyltransferase|serine hydroxymethyltransferase, cytosolic|serine methylase |
Swissprots | B4DPM9 D3DXD0 Q9UMD1 Q96HY0 P34896 Q9UMD2 |
Accessions | CAB54842 CAB54843 CAB54844 EAW55637 EAW55638 EAW55639 EAW55640 EAW55641 EAW55642 EAW55643 P34896 AF017065 AAC39726 AK223552 BAD97272 AK298415 BAG60641 AK302834 BAG64027 AU185281 BC007979 AAH07979 BC022874 AAH22874 BC038598 AAH38598 BM792235 DB451683 DQ893242 ABM84168 EU176779 ABW03580 L11931 AAA63257 L23928 AAA36018 Y14485 CAB54838 Y14486 CAB54839 Y14488 CAB54841 XM_005256767 XP_005256824 XM_011523992 XP_011522294 NM_001281786 NP_001268715 NM_004169 NP_004160 NM_148918 NP_683718 |
Function | Interconversion of serine and glycine. |
Subcellular Location | Cytoplasm. |
Top Pathways | Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Cyanoamino acid metabolism, Biosynthesis of amino acids, Carbon metabolism |
cSHMT CRISPR/Cas9 KO Plasmid (h) - sc-403678 from Santa Cruz Biotechnology
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cSHMT HDR Plasmid (h) - sc-403678-HDR from Santa Cruz Biotechnology
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cSHMT Double Nickase Plasmid (h) - sc-403678-NIC from Santa Cruz Biotechnology
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cSHMT Double Nickase Plasmid (h2) - sc-403678-NIC-2 from Santa Cruz Biotechnology
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cSHMT CRISPR Activation Plasmid (h) - sc-403678-ACT from Santa Cruz Biotechnology
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cSHMT CRISPR Activation Plasmid (h2) - sc-403678-ACT-2 from Santa Cruz Biotechnology
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cSHMT Lentiviral Activation Particles (h) - sc-403678-LAC from Santa Cruz Biotechnology
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cSHMT Lentiviral Activation Particles (h2) - sc-403678-LAC-2 from Santa Cruz Biotechnology
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cSHMT siRNA (h) - sc-40940 from Santa Cruz Biotechnology
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cSHMT shRNA Plasmid (h) - sc-40940-SH from Santa Cruz Biotechnology
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cSHMT shRNA (h) Lentiviral Particles - sc-40940-V from Santa Cruz Biotechnology
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SHMT1 RNAi - H00006470-R01 from Novus Biologicals
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SHMT1 RNAi - H00006470-R02 from Novus Biologicals
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MISSION® esiRNA - EHU159081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19308 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19308 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06930 from Sigma-Aldrich
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SHMT1 siRNA (Human) - CRH4373 from Cohesion Biosciences
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SHMT1 - MBS8216558 from MyBioSource
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shRNA set against Human SHMT1 (NM_004169.3) - SHH407168 from Creative biogene
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shRNA set against Human SHMT1(NM_148918.1) - SHR224364 from Creative biogene
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shRNA set against Human SHMT1(NM_004169.3) - SHR224464 from Creative biogene
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Human SHMT1 siRNA - orb264875 from Biorbyt
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SHMT1 shRNA Plasmid (Human) - CHH4373 from Cohesion Biosciences
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SHMT1 miRNA 3'UTR clone - MiUTR1H-09381 from Creative biogene
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