SHMT1

Gene Symbol SHMT1
Entrez Gene 6470
Alt Symbol CSHMT, SHMT
Species Human
Gene Type protein-coding
Description serine hydroxymethyltransferase 1 (soluble)
Other Description cytoplasmic serine hydroxymethyltransferase|glycine hydroxymethyltransferase|serine hydroxymethyltransferase, cytosolic|serine methylase
Swissprots B4DPM9 D3DXD0 Q9UMD1 Q96HY0 P34896 Q9UMD2
Accessions CAB54842 CAB54843 CAB54844 EAW55637 EAW55638 EAW55639 EAW55640 EAW55641 EAW55642 EAW55643 P34896 AF017065 AAC39726 AK223552 BAD97272 AK298415 BAG60641 AK302834 BAG64027 AU185281 BC007979 AAH07979 BC022874 AAH22874 BC038598 AAH38598 BM792235 DB451683 DQ893242 ABM84168 EU176779 ABW03580 L11931 AAA63257 L23928 AAA36018 Y14485 CAB54838 Y14486 CAB54839 Y14488 CAB54841 XM_005256767 XP_005256824 XM_011523992 XP_011522294 NM_001281786 NP_001268715 NM_004169 NP_004160 NM_148918 NP_683718
Function Interconversion of serine and glycine.
Subcellular Location Cytoplasm.
Top Pathways Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, Cyanoamino acid metabolism, Biosynthesis of amino acids, Carbon metabolism

SHMT1 Antibody - 12612 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10885)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using SHMT1 Antibody.

cSHMT (A-2) - sc-365203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cSHMT (A-2): sc-365203. Western blot analysis of cSHMT expression in non-transfected: sc-117752 (A) and human cSHMT transfected: sc-115685 (B) 293T whole cell lysates.

cSHMT (D-20) - sc-25060 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cSHMT (D-20): sc-25060. Western blot analysis of cSHMT expression in mouse liver tissue extract.

cSHMT (C-20) - sc-25061 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
cSHMT (C-20): sc-25061. Western blot analysis of cSHMT expression in non-transfected: sc-117752 (A) and human cSHMT transfected: sc-115685 (B) 293T whole cell lysates.

cSHMT (H-75) - sc-292885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

cSHMT (S-W6) - sc-100849 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
cSHMT (S-W6): sc-100849. Western blot analysis of cSHMT expression in non-transfected 293T: sc-117752 (A), human cSHMT transfected 293T: sc-115685 (B) and Hep G2 (C) whole cell lysates.

cSHMT (M-76) - sc-292886 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
cSHMT (M-76): sc-292886. Western blot analysis of cSHMT expression in Hep G2 (A), c4 (B) and A549 (D) whole cell lysates and mouse liver tissue extract (C).

cSHMT (F-9) - sc-514410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
cSHMT (F-9): sc-514410. Western blot analysis of cSHMT expression in HeLa (A) and Hep G2 (B) whole cell lysates and human liver (C) and human kidney (D) tissue extracts.

Anti-SHMT1 antibody - ab55736 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HeLa cells stained with ab55736 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab55736, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-SHMT1 antibody - ab103143 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SHMT1 antibody (ab103143) at 1/500 dilution + Human liver lysate at 50 µg

Anti-SHMT1 antibody - ab123416 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SHMT1 antibody (ab123416) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-SHMT1 antibody [4F9] - ab115665 from Abcam

Host Mouse
Clonality Monoclonal
Clone 4F9
Anti-SHMT1 antibody [4F9] (ab115665) at 1/500 dilution + HeLa cell lysate

Anti-SHMT / SHMT1 Antibody (aa1-483) - LS-C132099 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, APC) - LS-C269370 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, AP) - LS-C269371 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, Biotin) - LS-C269372 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, FITC) - LS-C269373 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, Azide-free, HRP) - LS-C269374 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa19-47, PE) - LS-C269375 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa374-483, Azide-free) - LS-C328657 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SHMT / SHMT1 Antibody (aa18-47) - LS-C325101 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SHMT / SHMT1 Antibody (aa35-84) - LS-C116361 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SHMT1 antibody LS-C116361 Western blot of A549 cell lysate.

Anti-SHMT / SHMT1 Antibody (aa19-47) - LS-C161077 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SHMT1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SHMT / SHMT1 Antibody (aa453-483) - LS-C290901 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human SHMT1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-SHMT1 antibody used for IP at 6 ug per reaction. SHMT1 was also immunoprecipitated by rabbit anti-SHMT1 antibody BL15560. For blotting immunoprecipitated SHMT1, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-SHMT / SHMT1 Antibody (clone 4F9) IHC-plus™ - LS-B4417 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4F9
Anti-SHMT1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4417 concentration 5 ug/ml.
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