EPOR

Gene Symbol	EPOR
Entrez Gene	2057
Alt Symbol	EPO-R
Species	Human
Gene Type	protein-coding
Description	erythropoietin receptor
Other Description	-
Swissprots	Q2M205 B2RCG4 P19235 Q15443
Accessions	AAA52392 AAA52393 AAB23271 AAB34703 ABX71216 AFM52330 AFM52331 EAW84205 EAW84206 EAW84207 EAW84208 P19235 AK315097 BAG37561 BC019092 BC112153 AAI12154 BC143697 BC143698 BC143700 BU619338 M34986 AAA52401 M60459 AAA52403 X57282 CAA40550 X97671 CAA66260 NM_000121 NP_000112 NR_033663
Function	Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EPOR / EPO Receptor ELISA Kit (Sandwich ELISA) - LS-F3985 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.064 ng/ml Range 92.44-5333 pg/ml

Rat EPOR / EPO Receptor ELISA Kit (Sandwich ELISA) - LS-F5452 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 27.1 pg/ml Range 92.44-5333 pg/ml

Mouse/Human/Rat Phospho-EPOR / EPO Receptor (Tyr368) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1356 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 92.44-5333 pg/ml

Mouse/Human/Rat EPOR / EPO Receptor ELISA Kit (Cell-Based ELISA) - LS-F1971 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 92.44-5333 pg/ml

Human EPOR / EPO Receptor ELISA Kit (Sandwich ELISA) - LS-F11381 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 92.44-5333 pg/ml

Pig EPOR / EPO Receptor ELISA Kit (Sandwich ELISA) - LS-F11382 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 78 Range 92.44-5333 pg/ml

Human EPOR / Erythropoietin Receptor ELISA Kit - RAB0655 from Sigma-Aldrich Category ELISA Kit Prices $633.00 Sizes 1 kt

Human Erythropoietin R DuoSet ELISA - DY307 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Human Phospho-Erythropoietin R DuoSet IC ELISA, 2 Plate - DYC5200-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates)

Human Total Erythropoietin R DuoSet IC ELISA, 2 Plate - DYC963-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 78.10 - 5,000 pg/mL

Human Phospho-Erythropoietin R (Y426) DuoSet IC ELISA, 2 Plt - DYC6926-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 156.00 - 10,000 pg/mL

Erythropoietin Receptor ELISA Pair Set - orb145942 from Biorbyt Category ELISA Kit Prices $646.00, $1,369.00 Sizes 5 plates, 15 plates

Human EPOR ELISA Kit - abx151436 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human Erythropoietin Receptor ELISA Kit - abx053244 from Abbexa Category ELISA Kit

Erythropoietin Receptor, EPOR, Human, ELISA Kit - E-EL-H1399 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Erythropoietin Receptor (EPOR), Human, ELISA Kit - SEA027Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.057ng/mL Range 0.156-10ng/mL

Erythropoietin receptor, EPOR, Human, ELISA Kit - CSB-E04537h from ARP American Research Products Category ELISA Kit Prices $450.00, $595.00, $596.00, $599.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 11.75 pg/ml Range 47 pg/ml-3000 pg/ml

Erythropoietin receptor, EPOR, Human, ELISA Kit - E0027h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 78-5000 pg/mL

Erythropoietin Receptor, Human, ELISA Kit - E01E0057 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Erythropoietin receptor, EPOR, Mouse, ELISA Kit - E-EL-M0472 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Erythropoietin Receptor, EPOR, Rabbit, ELISA Kit - E-EL-RB1529 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Erythropoietin Receptor, EPOR, Chicken, ELISA Kit - E-EL-Ch0507 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Erythropoietin Receptor, EPOR, Porcine, ELISA Kit - E-EL-P1489 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Erythropoietin Receptor, EPOR, Sheep, ELISA Kit - E-EL-S0654 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Erythropoietin Receptor, EPOR, Monkey, ELISA Kit - E-EL-MK0456 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

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