EPOR

Gene Symbol	EPOR
Entrez Gene	2057
Alt Symbol	EPO-R
Species	Human
Gene Type	protein-coding
Description	erythropoietin receptor
Other Description	-
Swissprots	Q2M205 B2RCG4 P19235 Q15443
Accessions	AAA52392 AAA52393 AAB23271 AAB34703 ABX71216 AFM52330 AFM52331 EAW84205 EAW84206 EAW84207 EAW84208 P19235 AK315097 BAG37561 BC019092 BC112153 AAI12154 BC143697 BC143698 BC143700 BU619338 M34986 AAA52401 M60459 AAA52403 X57282 CAA40550 X97671 CAA66260 NM_000121 NP_000112 NR_033663
Function	Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human EPO Receptor protein fragment - ab174067 from Abcam Category Protein Prices $372.00 Sizes 100 µg Source HEK 293 cells Species Human

EPO Receptor protein (Fc Chimera Active) - ab84001 from Abcam Category Protein Prices $386.00 Sizes 25 µg Source HEK 293 cells Species Human

EPO Receptor peptide - ab157523 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human EPO Receptor full length protein - ab131833 from Abcam Category Protein Source Wheat germ Species Human

Human EPO Receptor protein fragment - ab152367 from Abcam Category Protein Source Wheat germ Species Human

EPOR / EPO Receptor Antibody Blocking Peptide - LS-E4376 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EPOR / EPO Receptor Antibody Blocking Peptide - LS-E16244 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EPOR / EPO Receptor Antibody Blocking Peptide - LS-E16245 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Erythropoietin R Partial Recombinant Protein - H00002057-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Erythropoietin R Recombinant Protein - H00002057-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EPOR-Antibody-Center-Blocking-Peptide - BP16681c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Erythropoietin R Fc Chimera, CF - 963-ER-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human Erythropoietin R - 307-ER-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala25-Pro250

Recombinant Human Erythropoietin R, CF - 307-ER-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala25-Pro250

Human Erythropoietin Receptor protein - orb84170 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human Erythropoietin Receptor protein - orb82990 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human Erythropoietin Receptor protein - orb84353 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human Species Human

EPOr Blocking Peptide - 33R-1978 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human EPOR Protein - abx066461 from Abbexa Category Protein Source E.coli Species Human

Erythropoietin receptor - H00002057-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Erythropoietin receptor - H00002057-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Erythropoietin receptor - H00002057-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Erythropoietin receptor - H00002057-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Erythropoietin Receptor (EPOR), Human - 20-6073 from ARP American Research Products Category Protein Prices $479.00 Sizes 50 µg Source E.coli Species Human

Erythropoietin R Recombinant Protein - 96-278 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

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