RGN

Gene Symbol RGN
Entrez Gene 9104
Alt Symbol GNL, HEL-S-41, RC, SMP30
Species Human
Gene Type protein-coding
Description regucalcin
Other Description epididymis secretory protein Li 41|gluconolactonase|senescence marker protein 30
Swissprots A4FTW1 Q53FC9 A8K271 Q5JRR5 Q15493
Accessions EAW59279 EAW59280 Q15493 AB028125 BAA78693 AB032064 BAA84082 AK223360 BAD97080 AK290136 BAF82825 BC050371 AAH50371 BC058880 BC073173 AAH73173 D31815 BAA06602 EU794655 ACJ13709 HY260443 XM_006724567 XP_006724630 XM_006724568 XP_006724631 NM_001282848 NP_001269777 NM_001282849 NP_001269778 NM_004683 NP_004674 NM_152869 NP_690608
Function Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Pentose phosphate pathway, Ascorbate and aldarate metabolism, Carbon metabolism, Degradation of aromatic compounds

SMP30 (E-11) - sc-390098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SMP30 (E-11): sc-390098. Western blot analysis of SMP30 expression in Hep G2 whole cell lysate (A) and human brain (B) and mouse brain (C) tissue extracts.

SMP30 (G-10) - sc-374019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SMP30 (G-10): sc-374019. Western blot analysis of SMP30 expression in Hep G2 whole cell lysate.

SMP30 (H-4) - sc-377184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SMP30 (H-4): sc-377184. Western blot analysis of SMP30 expression in non-transfected 293T: sc-117752 (A), human SMP30 transfected 293T: sc-111590 (B) and Hep G2 (C) whole cell lysates.

SMP30 (17) - sc-130344 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SMP30 (17): sc-130344. Western blot analysis of SMP30 expression in mouse liver tissue extract.

SMP30 (C-16) - sc-25951 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of SMP30 expression in mouse liver tissue extract (A,B). Antibodies tested include SMP30 (K-18): sc-25950 (A) and SMP30 (C-16): sc-25951 (B).

SMP30 (FL-299) - sc-292770 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SMP30 (FL-299): sc-292770. Western blot analysis of SMP30 expression in human liver (A) and mouse liver (B) tissue extracts.

SMP30 (K-18) - sc-25950 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of SMP30 expression in mouse liver tissue extract (A,B). Antibodies tested include SMP30 (K-18): sc-25950 (A) and SMP30 (C-16): sc-25951 (B).

Anti-Regucalcin antibody - ab67014 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Regucalcin antibody (ab67014) at 1/500 dilutionLane 1 : Regucalcin transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-Regucalcin antibody [17] - ab67336 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 17
Anti-Regucalcin antibody [17] (ab67336) at 1/1000 dilution + Human recombinant Regucalcin protein

Anti-RGN / Regucalcin Antibody - LS-C137561 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Regucalcin Antibody - NBP1-80849 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Regucalcin Antibody [NBP1-80849] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

Regucalcin Antibody - NBP1-80850 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Regucalcin Antibody [NBP1-80850] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

Regucalcin Antibody - H00009104-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: Regucalcin Antibody [H00009104-B01] - RGN MaxPab polyclonal antibody (B01), Lot # 08101 WULz. Western Blot analysis of RGN expression in human liver.

Regucalcin Antibody - H00009104-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Regucalcin Antibody [H00009104-B01P] - RGN MaxPab polyclonal antibody. Western Blot analysis of RGN expression in human liver.

Regucalcin Antibody (4B9) - H00009104-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B9
Western Blot: Regucalcin Antibody (4B9) [H00009104-M04] - Analysis of RGN expression in transfected 293T cell line by RGN monoclonal antibody (M04), clone 4B9. Lane 1: RGN transfected lysatE (33.3 KDa). Lane 2: Non-transfected lysate.

Regucalcin/SMP30 Polyclonal Antibody - bs-2665R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-Regucalcin/SMP30 Polyclonal Antibody, Unconjugated (bs-2665R) at 1:200 followed by conjugation to the secondary antibody and DAB stainin

Monoclonal Anti-RGN, (C-terminal) antibody produced in mouse - SAB1402448 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B9
<B>Immunoblotting</B><BR/>Monoclonal Anti-RGN, antibody produced in mouse, clone 4B9, purified immunoglobulin: <B>Cat. No. SAB1402448</B>: Antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

Anti-RGN antibody produced in rabbit - HPA029102 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RGN: <B>Cat. No. HPA029102</B>: Immunohistochemical staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Anti-RGN antibody produced in rabbit - HPA029103 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RGN: <B>Cat. No. HPA029103</B>: Immunohistochemical staining of human adrenal gland shows strong cytoplasmic and nuclear positivity in cortical cells.

Anti-RGN antibody produced in mouse - SAB1400333 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-RGN, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400333</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~33.3 kDa using human liver lysate.

Anti-RGN (96-110) antibody produced in rabbit - SAB1100641 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-RGN (96-110) : <B>Cat. No. SAB1100641</B>: Immunofluorescence of HUVEC cells using RGN (96-110) , Cat. No. SAB1100641 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Regucalcin antibody - orb6995 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded rat brain tissue using Regucalcin antibody (dilution at 1:200)

SMP30 antibody - 10R-10270 from Fitzgerald

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone M78640

SMP30 antibody - 70R-21671 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Regucalcin/SMP30 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-2665R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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