| Gene Symbol |
PSMB6
|
| Entrez Gene |
5694
|
| Alt Symbol |
DELTA, LMPY, Y
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) subunit, beta type, 6
|
| Other Description |
PSY large multifunctional protease Y|macropain delta chain|multicatalytic endopeptidase complex delta chain|proteasome catalytic subunit 1|proteasome delta chain|proteasome subunit Y|proteasome subunit beta type-6|proteasome subunit delta
|
| Swissprots |
Q96J55 P28072
|
| Accessions |
EAW90407 P28072 AK311768 BAG34711 BC000835 AAH00835 BF671774 BM553399 BQ691763 BT009809 AAP88811 BU848746 CR457065 CAG33346 D29012 BAA06098 DQ891216 ABM82142 DQ894399 ABM85325 X61971 CAA43963 NM_001270481 NP_001257410 NM_002798 NP_002789
|
| Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Top Pathways |
Proteasome
|
![Western Blot: Proteasome 20S beta 6 Overexpression Lysate (Adult Normal) [NBL1-14881] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Proteasome 20S beta 6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4340_Proteasome%252020S%2520beta%25206%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-14881-img0002.jpg)