Gene Symbol | PSMB6 |
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Entrez Gene | 5694 |
Alt Symbol | DELTA, LMPY, Y |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) subunit, beta type, 6 |
Other Description | PSY large multifunctional protease Y|macropain delta chain|multicatalytic endopeptidase complex delta chain|proteasome catalytic subunit 1|proteasome delta chain|proteasome subunit Y|proteasome subunit beta type-6|proteasome subunit delta |
Swissprots | Q96J55 P28072 |
Accessions | EAW90407 P28072 AK311768 BAG34711 BC000835 AAH00835 BF671774 BM553399 BQ691763 BT009809 AAP88811 BU848746 CR457065 CAG33346 D29012 BAA06098 DQ891216 ABM82142 DQ894399 ABM85325 X61971 CAA43963 NM_001270481 NP_001257410 NM_002798 NP_002789 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens. |
Subcellular Location | Cytoplasm. Nucleus. |
Top Pathways | Proteasome |
PSMB6 CRISPR/Cas9 KO Plasmid (h) - sc-404679 from Santa Cruz Biotechnology
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PSMB6 HDR Plasmid (h) - sc-404679-HDR from Santa Cruz Biotechnology
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PSMB6 Double Nickase Plasmid (h) - sc-404679-NIC from Santa Cruz Biotechnology
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PSMB6 Double Nickase Plasmid (h2) - sc-404679-NIC-2 from Santa Cruz Biotechnology
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PSMB6 CRISPR Activation Plasmid (h) - sc-404679-ACT from Santa Cruz Biotechnology
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PSMB6 CRISPR Activation Plasmid (h2) - sc-404679-ACT-2 from Santa Cruz Biotechnology
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PSMB6 Lentiviral Activation Particles (h) - sc-404679-LAC from Santa Cruz Biotechnology
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PSMB6 Lentiviral Activation Particles (h2) - sc-404679-LAC-2 from Santa Cruz Biotechnology
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PSMB6 siRNA (h) - sc-76271 from Santa Cruz Biotechnology
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PSMB6 shRNA Plasmid (h) - sc-76271-SH from Santa Cruz Biotechnology
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PSMB6 shRNA (h) Lentiviral Particles - sc-76271-V from Santa Cruz Biotechnology
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Proteasome 20S beta 6 RNAi - H00005694-R01 from Novus Biologicals
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MISSION® esiRNA - EHU030181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17603 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17603 from Sigma-Aldrich
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PSMB6 siRNA (Human) - CRH3841 from Cohesion Biosciences
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shRNA set against Human PSMB6 (NM_002798.2) - SHH385216 from Creative biogene
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Human PSMB6 siRNA - orb264343 from Biorbyt
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PSMB6 shRNA Plasmid (Human) - CHH3841 from Cohesion Biosciences
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PSMB6 miRNA 3'UTR clone - MiUTR3H-03256 from Creative biogene
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