Gene Symbol | SPTB |
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Entrez Gene | 6710 |
Alt Symbol | EL3, HS2, HSPTB1, SPH2 |
Species | Human |
Gene Type | protein-coding |
Description | spectrin, beta, erythrocytic |
Other Description | beta-I spectrin|membrane cytoskeletal protein|spectrin beta chain, erythrocyte|spectrin beta chain, erythrocytic |
Swissprots | Q15510 Q15519 P11277 |
Accessions | AAC02786 AAC02787 AAC02788 AAC02789 AAC02790 AAC02791 AAC02792 AAC02793 ABL96684 EAW80875 EAW80876 EAW80877 EAW80878 EAW80879 EAW80880 EAW80881 EAW80882 P11277 AB209415 BAD92652 AF465439 AAL73492 AK094815 AK126627 BC010434 BC136284 AAI36285 BC136285 AAI36286 BM681142 BX248270 CAD62598 CN370674 DQ588282 J05500 AAA60578 M18054 AAA60572 M37884 AAA63259 M37885 AAA60571 M57948 S42560 AAB22889 X59510 CAA42097 X59511 CAA42098 XM_005268023 XP_005268080 XM_011537105 XP_011535407 NM_000347 NP_000338 NM_001024858 NP_001020029 |
Function | Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. |
Subcellular Location | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. |
spectrin β I siRNA (h) - sc-36547 from Santa Cruz Biotechnology
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spectrin β 1 shRNA Plasmid (h) - sc-36547-SH from Santa Cruz Biotechnology
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spectrin β 1 shRNA (h) Lentiviral Particles - sc-36547-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU139801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20540 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20540 from Sigma-Aldrich
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SPTB siRNA (Human) - CRH4579 from Cohesion Biosciences
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SPTB - MBS828052 from MyBioSource
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shRNA set against Human SPTB (NM_000347.5) - SHH417496 from Creative biogene
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Human SPTB siRNA - orb265081 from Biorbyt
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SPTB shRNA Plasmid (Human) - CHH4579 from Cohesion Biosciences
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SPTB miRNA 3'UTR clone - MiUTR3H-02129 from Creative biogene
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