SPTB

Gene Symbol SPTB
Entrez Gene 6710
Alt Symbol EL3, HS2, HSPTB1, SPH2
Species Human
Gene Type protein-coding
Description spectrin, beta, erythrocytic
Other Description beta-I spectrin|membrane cytoskeletal protein|spectrin beta chain, erythrocyte|spectrin beta chain, erythrocytic
Swissprots Q15510 Q15519 P11277
Accessions AAC02786 AAC02787 AAC02788 AAC02789 AAC02790 AAC02791 AAC02792 AAC02793 ABL96684 EAW80875 EAW80876 EAW80877 EAW80878 EAW80879 EAW80880 EAW80881 EAW80882 P11277 AB209415 BAD92652 AF465439 AAL73492 AK094815 AK126627 BC010434 BC136284 AAI36285 BC136285 AAI36286 BM681142 BX248270 CAD62598 CN370674 DQ588282 J05500 AAA60578 M18054 AAA60572 M37884 AAA63259 M37885 AAA60571 M57948 S42560 AAB22889 X59510 CAA42097 X59511 CAA42098 XM_005268023 XP_005268080 XM_011537105 XP_011535407 NM_000347 NP_000338 NM_001024858 NP_001020029
Function Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
Subcellular Location Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

spectrin β I (C-18) - sc-7466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
spectrin β I (C-18): sc-7466. Western blot analysis of spectrinβ I expression in rat heart tissue extract.

spectrin β I (H-60) - sc-28271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
spectrin β I (H-60): sc-28271. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing membrane and cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

spectrin β I (4C3) - sc-58851 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
spectrin β I (4C3): sc-58851. Western blot analysis of spectrin b I expression in HEL 92.1.7 whole cell lysate.

spectrin β I (N-19) - sc-7467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
spectrin β I (N-19): sc-7467. Western blot analysis of spectrin β I expression in rat cerebellum tissue extract.

spectrin β I (VD4) - sc-53901 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
spectrin β I (VD4): sc-53901. Western blot analysis of spectrin β I expression in HEL 92.1.7 (A) and TF-1 (B) whole cell lysates and rat skeletal muscle tissue extract (C).

spectrin β I (6D772) - sc-73053 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-beta 1 Spectrin antibody [4C3] - ab2808 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C3
Immunocytochemistry/Immunofluorescence analysis of beta 1 Spectrin (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were incubated with ab2808 in 3% BSA-PBS at a dilution of 1:20 and incubated overnight at 4 ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody in PBS at room temperature in the dark. F-actin (red) was stained with a flourescent red phalloidin and nuclei (blue) were stained with Hoechst or DAPI. Images were taken at a magnification of 60x.

Anti-beta 1 Spectrin antibody [DB2] - ab86185 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DB2

Anti-beta 1 Spectrin antibody [EPR6259] - ab129065 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6259
Anti-beta 1 Spectrin antibody [EPR6259] (ab129065) at 1/1000 dilution + Red blood cell lysate at 10 µgSecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-beta 1 Spectrin antibody [RBC2/3D5] - ab49567 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone RBC2/3D5

Anti-SPTB / Beta Spectrin Antibody - LS-C89232 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-SPTB / Beta Spectrin Antibody - LS-C89229 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-SPTB / Beta Spectrin Antibody (clone DB2) - LS-C202547 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DB2

Anti-SPTB / Beta Spectrin Antibody (clone DB2) - LS-C132174 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DB2

Anti-SPTB / Beta Spectrin Antibody (clone RBC2/3D5) - LS-C189585 from LifeSpan Bioscience

Prices $605.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone RBC2/3D5

Anti-SPTB / Beta Spectrin Antibody (Internal, clone EPR6259) - LS-C152466 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6259
Western blot analysis on red blood cell lysate using anti-SPTB antibody.

Spectrin beta 1 Antibody (4C3) - NB300-574 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C3
Western Blot: Spectrin beta 1 Antibody (4C3) [NB300-574] - Analysis of 25 ug of Hela cell lysates.

Spectrin beta 1 Antibody - NBP1-90350 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Spectrin beta 1 Antibody [NBP1-90350] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Spectrin beta 1 Antibody - NBP1-87596 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Spectrin beta 1 Antibody [NBP1-87596] - Staining of human bone marrow shows strong cytoplasmic positivity in bone marrow poietic cells.

Spectrin alpha 1 Antibody (B12G3) - NB100-64724 from Novus Biologicals

Prices $279.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone B12G3

Anti-SPTB antibody produced in rabbit - HPA003394 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPTB: <B>Cat. No. HPA003394</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human bone marrow tissue showing cytoplasmic and/or membranous staining of bone marrow poetic cells.

Anti-SPTB antibody produced in rabbit - HPA003398 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SPTB: <B>Cat. No. HPA003398</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human bone marrow tissue showing cytoplasmic and/or membranous staining of bone marrow poietic cells as well as positive staining of erythrocytes.

SPTB Antibody (OAAD00200) - OAAD00200 from Aviva Systems Biology

Prices $255.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Spe 1/2

SPTB Antibody (OASA03293) - OASA03293 from Aviva Systems Biology

Prices $355.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal
Clone B12G3

CD59 antibody [8D2B8] - GTX60658 from GeneTex

Prices $319.00
Sizes 100 μg
Host Mouse
Clonality Monoclonal
Clone 8D2B8
Anti-CD59 antibody [8D2B8] used in ELISA. GTX60658
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