| Gene Symbol |
DUSP22
|
| Entrez Gene |
56940
|
| Alt Symbol |
JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dual specificity phosphatase 22
|
| Other Description |
JNK-stimulating phosphatase 1|JNK-stimulatory phosphatase-1|MAP kinase phosphatase x|dual specificity protein phosphatase 22|homolog of mouse dual specificity phosphatase LMW-DSP2|low molecular weight dual specificity phosphatase 2|mitogen-activated protein kinase phosphatase x
|
| Swissprots |
Q96AR1 Q9NRW4 Q59GW2 B4DK56 Q5VWR2
|
| Accessions |
CAI93197 EAW53895 Q9NRW4 AB208997 BAD92234 AF165519 AAF86649 AF424702 AAL18850 AK000383 AK074410 AK128760 AK296402 BAG59068 AK310653 AY249859 AAP76376 BC009209 BC016844 AAH16844 BC022847 AAH22847 BX107497 BX362191 BX648953 DA950312 DB177174 DQ786251 DQ893393 ABM84319 DQ896715 ABM87714 XM_011514757 XP_011513059 NM_001286555 NP_001273484 NM_020185 NP_064570 NR_104473 NR_104474 NR_104475
|
| Function |
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:11717427}.
|