Gene Symbol | DUSP22 |
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Entrez Gene | 56940 |
Alt Symbol | JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 22 |
Other Description | JNK-stimulating phosphatase 1|JNK-stimulatory phosphatase-1|MAP kinase phosphatase x|dual specificity protein phosphatase 22|homolog of mouse dual specificity phosphatase LMW-DSP2|low molecular weight dual specificity phosphatase 2|mitogen-activated protein kinase phosphatase x |
Swissprots | Q96AR1 Q9NRW4 Q59GW2 B4DK56 Q5VWR2 |
Accessions | CAI93197 EAW53895 Q9NRW4 AB208997 BAD92234 AF165519 AAF86649 AF424702 AAL18850 AK000383 AK074410 AK128760 AK296402 BAG59068 AK310653 AY249859 AAP76376 BC009209 BC016844 AAH16844 BC022847 AAH22847 BX107497 BX362191 BX648953 DA950312 DB177174 DQ786251 DQ893393 ABM84319 DQ896715 ABM87714 XM_011514757 XP_011513059 NM_001286555 NP_001273484 NM_020185 NP_064570 NR_104473 NR_104474 NR_104475 |
Function | Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:11717427}. |
Human DUSP22 full length protein - ab163442 from Abcam
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Human DUSP22 full length protein - ab180296 from Abcam
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Human DUSP22 protein fragment - ab163443 from Abcam
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DUSP22 / JSP 1 Antibody Blocking Peptide - LS-E21381 from LifeSpan Bioscience
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DUSP22 / JSP 1 Antibody Blocking Peptide - LS-E29193 from LifeSpan Bioscience
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DUSP22 / JSP 1 Antibody Blocking Peptide - LS-E29194 from LifeSpan Bioscience
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DUSP22 / JSP 1 Antibody Blocking Peptide - LS-E29300 from LifeSpan Bioscience
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DUSP22 Partial Recombinant Protein - H00056940-Q01 from Novus Biologicals
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DUSP22 Recombinant Protein - H00056940-P01 from Novus Biologicals
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DUSP22 protein (His tag) - 80R-3817 from Fitzgerald
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MAP Kinase Phosphatase X (1-184, His-tag) - AR51504PU-N from Acris Antibodies
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MAP Kinase Phosphatase X (1-184, His-tag) - AR51504PU-S from Acris Antibodies
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MAP Kinase Phosphatase X - H00056940-P01-10 from Acris Antibodies
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MAP Kinase Phosphatase X - H00056940-P01-25 from Acris Antibodies
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MAP Kinase Phosphatase X - H00056940-Q01-10 from Acris Antibodies
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MAP Kinase Phosphatase X - H00056940-Q01-25 from Acris Antibodies
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DUSP22,1-184aa, Human, His tag, E.coli - 01-P2684 from ARP American Research Products
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DUSP22 fusion protein - Ag9734 from Proteintech Group
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DUSP22 fusion protein - Ag9831 from Proteintech Group
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Recombinant Human Dual Specificity Phosphatase 22, GST-tagged, Active - DUSP22-459H from Creative Biomart
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Recombinant Human DUSP22, GST-tagged - DUSP22-12213H from Creative Biomart
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Recombinant Human DUSP22, His-tagged - DUSP22-191H from Creative Biomart
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Recombinant Human DUSP22 (Active), GST-tagged - DUSP22-1514H from Creative Biomart
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DUSP22 Protein, 250 µg - 14-641M from EMD Millipore
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DUSP22 Protein, 10 µg - 14-641 from EMD Millipore
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