| Gene Symbol |
PSMD5
|
| Entrez Gene |
5711
|
| Alt Symbol |
S5B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
|
| Other Description |
26S protease subunit S5 basic|26S proteasome non-ATPase regulatory subunit 5|26S proteasome subunit S5B
|
| Swissprots |
Q16401 Q15045 B4DZM8 Q4VXG8
|
| Accessions |
EAW87471 Q16401 AK001065 AK026925 AK291051 BAF83740 AK303007 BAG64140 BC014478 AAH14478 BM835267 D31889 BAA06687 DQ892085 ABM83011 DQ895279 ABM86205 HY023459 S79862 AAB35397 XM_011518866 XP_011517168 XM_011518867 XP_011517169 NM_001270427 NP_001257356 NM_005047 NP_005038
|
| Function |
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5. {ECO:0000269|PubMed:19412159, ECO:0000269|PubMed:19490896}.
|