Gene Symbol | PSMD5 |
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Entrez Gene | 5711 |
Alt Symbol | S5B |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
Other Description | 26S protease subunit S5 basic|26S proteasome non-ATPase regulatory subunit 5|26S proteasome subunit S5B |
Swissprots | Q16401 Q15045 B4DZM8 Q4VXG8 |
Accessions | EAW87471 Q16401 AK001065 AK026925 AK291051 BAF83740 AK303007 BAG64140 BC014478 AAH14478 BM835267 D31889 BAA06687 DQ892085 ABM83011 DQ895279 ABM86205 HY023459 S79862 AAB35397 XM_011518866 XP_011517168 XM_011518867 XP_011517169 NM_001270427 NP_001257356 NM_005047 NP_005038 |
Function | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5. {ECO:0000269|PubMed:19412159, ECO:0000269|PubMed:19490896}. |
PSMD5 CRISPR/Cas9 KO Plasmid (h) - sc-417717 from Santa Cruz Biotechnology
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PSMD5 HDR Plasmid (h) - sc-417717-HDR from Santa Cruz Biotechnology
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PSMD5 Double Nickase Plasmid (h) - sc-417717-NIC from Santa Cruz Biotechnology
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PSMD5 Double Nickase Plasmid (h2) - sc-417717-NIC-2 from Santa Cruz Biotechnology
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PSMD5 CRISPR Activation Plasmid (h) - sc-417717-ACT from Santa Cruz Biotechnology
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PSMD5 CRISPR Activation Plasmid (h2) - sc-417717-ACT-2 from Santa Cruz Biotechnology
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PSMD5 Lentiviral Activation Particles (h) - sc-417717-LAC from Santa Cruz Biotechnology
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PSMD5 Lentiviral Activation Particles (h2) - sc-417717-LAC-2 from Santa Cruz Biotechnology
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PSMD5 siRNA (h) - sc-92791 from Santa Cruz Biotechnology
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PSMD5 shRNA Plasmid (h) - sc-92791-SH from Santa Cruz Biotechnology
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PSMD5 shRNA (h) Lentiviral Particles - sc-92791-V from Santa Cruz Biotechnology
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Proteasome 26S S5 RNAi - H00005711-R01 from Novus Biologicals
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MISSION® esiRNA - EHU067701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17623 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17623 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10695 from Sigma-Aldrich
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PSMD5 siRNA (Human) - CRH3857 from Cohesion Biosciences
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shRNA set against Human PSMD5 (NM_005047.3) - SHH385456 from Creative biogene
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PSMD5 shRNA Plasmid (Human) - CHH3857 from Cohesion Biosciences
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PSMD5 miRNA 3'UTR clone - MiUTR3H-06814 from Creative biogene
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