EPHA7

Gene Symbol	EPHA7
Entrez Gene	2045
Alt Symbol	EHK-3, EHK3, EK11, HEK11
Species	Human
Gene Type	protein-coding
Description	EPH receptor A7
Other Description	EPH homology kinase 3|EPH-like kinase 11|Eph homology kinase-3|ephrin type-A receptor 7|receptor protein-tyrosine kinase HEK11|tyrosine-protein kinase receptor EHK-3
Swissprots	B7ZLJ9 Q8N368 A0AUX7 Q15375 Q5VTU0 Q59G40 B2R8W1 B7ZLK0 Q9H124
Accessions	CAT16938 CCQ43263 EAW48518 EAW48519 EAW48520 EAW48521 Q15375 AB209269 BAD92506 AK313529 BAG36308 AL699163 BC027940 AAH27940 BC126125 AAI26126 BC126151 AAI26152 BC143857 AAI43858 BC143858 AAI43859 BM677016 DA503795 L36642 AAA74243 XM_005248669 XP_005248726 XM_005248671 XP_005248728 NM_001288629 NP_001275558 NM_001288630 NP_001275559 NM_004440 NP_004431
Function	Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of E
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Widely expressed.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EphA7 (G-7) - sc-365647 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

EphA7 (F-10) - sc-393974 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

EphA7 (E-7) - sc-393973 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

EphA7 (C-19) - sc-918 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphA7 (H-55) - sc-25459 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphA7 (K-16) - sc-917 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EphA7 (A-18) - sc-1015 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 (phospho Y791) antibody - ab192585 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 antibody - ab176102 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 antibody - ab54640 from Abcam Host Mouse Clonality Monoclonal

Anti-Eph receptor A7 antibody - ab136095 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 antibody - ab93648 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 antibody - ab133888 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Eph receptor A7 antibody [6C8G7] - ab76372 from Abcam Prices $370.00 Sizes 100 µl Host Mouse Clonality Monoclonal Clone 6C8G7

Anti-Eph receptor A7 antibody - C-terminal - ab72060 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A6 Antibody (aa128-142) - LS-C6544 from LifeSpan Bioscience Prices $385.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A6 Antibody (Extracellular Domain) - LS-C125532 from LifeSpan Bioscience Prices $635.00 Sizes 100 µg Host Rat Clonality Monoclonal

Anti-EPHA7 / EPH Receptor A6 Antibody (aa128-142) - LS-C147869 from LifeSpan Bioscience Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, APC) - LS-C222452 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, Biotin) - LS-C222453 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, AP) - LS-C222451 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, Azide-free, HRP) - LS-C222455 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, FITC) - LS-C222454 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa904-933, PE) - LS-C222456 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EPHA7 / EPH Receptor A7 Antibody (aa112-140, AP) - LS-C222457 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Search more