| Gene Symbol |
RAB32
|
| Entrez Gene |
10981
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAB32, member RAS oncogene family
|
| Other Description |
ras-related protein Rab-32
|
| Swissprots |
Q13637
|
| Accessions |
EAW47833 Q13637 AF498958 AAM21106 AK312202 BAG35135 BC015061 AAH15061 BT020016 AAV38819 DQ892882 ABM83808 DQ896131 ABM87130 U59878 AAB02833 U71127 AAB09599 NM_006834 NP_006825
|
| Function |
Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. {ECO:0000269|PubMed:12186851, ECO:0000269|PubMed:21255211}.
|
| Subcellular Location |
Mitochondrion. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
|
| Tissue Specificity |
Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung. {ECO:0000269|PubMed:11784320, ECO:0000269|PubMed:12186851}.
|
![Western Blot: RAB32 Overexpression Lysate (Adult Normal) [NBL1-15061] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAB32.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5916_RAB32%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15061-img0002.jpg)