Gene Symbol | RAB32 |
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Entrez Gene | 10981 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB32, member RAS oncogene family |
Other Description | ras-related protein Rab-32 |
Swissprots | Q13637 |
Accessions | EAW47833 Q13637 AF498958 AAM21106 AK312202 BAG35135 BC015061 AAH15061 BT020016 AAV38819 DQ892882 ABM83808 DQ896131 ABM87130 U59878 AAB02833 U71127 AAB09599 NM_006834 NP_006825 |
Function | Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. {ECO:0000269|PubMed:12186851, ECO:0000269|PubMed:21255211}. |
Subcellular Location | Mitochondrion. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. |
Tissue Specificity | Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung. {ECO:0000269|PubMed:11784320, ECO:0000269|PubMed:12186851}. |
Rab 32 CRISPR/Cas9 KO Plasmid (h) - sc-403733 from Santa Cruz Biotechnology
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Rab 32 HDR Plasmid (h) - sc-403733-HDR from Santa Cruz Biotechnology
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Rab 32 Double Nickase Plasmid (h) - sc-403733-NIC from Santa Cruz Biotechnology
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Rab 32 Double Nickase Plasmid (h2) - sc-403733-NIC-2 from Santa Cruz Biotechnology
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Rab 32 CRISPR Activation Plasmid (h) - sc-403733-ACT from Santa Cruz Biotechnology
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Rab 32 CRISPR Activation Plasmid (h2) - sc-403733-ACT-2 from Santa Cruz Biotechnology
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Rab 32 Lentiviral Activation Particles (h) - sc-403733-LAC from Santa Cruz Biotechnology
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Rab 32 Lentiviral Activation Particles (h2) - sc-403733-LAC-2 from Santa Cruz Biotechnology
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Rab 32 siRNA (h) - sc-95461 from Santa Cruz Biotechnology
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Rab 32 shRNA Plasmid (h) - sc-95461-SH from Santa Cruz Biotechnology
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Rab 32 shRNA (h) Lentiviral Particles - sc-95461-V from Santa Cruz Biotechnology
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RAB32 RNAi - H00010981-R01 from Novus Biologicals
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MISSION® esiRNA - EHU023031 from Sigma-Aldrich
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MISSION® siRNA - SIHK1914 from Sigma-Aldrich
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MISSION® siRNA - SIHK1912 from Sigma-Aldrich
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MISSION® siRNA - SIHK1913 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17832 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17832 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02827 from Sigma-Aldrich
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RAB32 siRNA (Human) - CRH7498 from Cohesion Biosciences
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RAB32 - MBS8215780 from MyBioSource
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shRNA set against Human RAB32 (NM_006834.3) - SHH388184 from Creative biogene
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shRNA set against Human RAB32(NM_006834.3) - SHR158834 from Creative biogene
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RAB32 shRNA Plasmid (Human) - CHH7498 from Cohesion Biosciences
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RAB32 miRNA 3'UTR clone - MiUTR1H-08554 from Creative biogene
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