FILIP1L

Gene Symbol FILIP1L
Entrez Gene 11259
Alt Symbol DOC-1, DOC1, GIP130, GIP90
Species Human
Gene Type protein-coding
Description filamin A interacting protein 1-like
Other Description 130 kDa GPBP-interacting protein|90 kDa GPBP-interacting protein|filamin A-interacting protein 1-like|protein down-regulated in ovarian cancer 1
Swissprots B2CNV7 Q6KFX7 Q2YDY5 B2CNV8 Q6KFX5 Q6KFX6 Q8IUM3 Q8N6Z0 Q4L180 Q13597
Accessions EAW79833 EAW79834 Q4L180 AF329092 AAN16206 AF514867 AAQ08177 AF514868 AAQ08178 AF514869 AAQ08179 AK096195 AK225855 AX776292 CAE11726 AX776294 CAE11727 AX776296 CAE11728 AX776298 CAE11729 AY642382 AAV34207 BC017987 BC020941 AAH20941 BC027860 AAH27860 BM674194 BP233250 DB080427 EU531865 ACB37436 EU531866 ACB37437 U53445 AAA98972 XM_006713486 XP_006713549 XM_011512371 XP_011510673 NM_001042459 NP_001035924 NM_001282793 NP_001269722 NM_001282794 NP_001269723 NM_014890 NP_055705 NM_182909 NP_878913
Function Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature. {ECO:0000269|PubMed:18794120}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:18794120}. Membrane {ECO:0000269|PubMed:18794120}. Nucleus {ECO:0000269|PubMed:18794120}.
Tissue Specificity Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer. {ECO:0000269|PubMed:18794120, ECO:0000269|PubMed:8314147}.

DOC1 CRISPR/Cas9 KO Plasmid (h) - sc-407358 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 HDR Plasmid (h) - sc-407358-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 Double Nickase Plasmid (h) - sc-407358-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 Double Nickase Plasmid (h2) - sc-407358-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 CRISPR Activation Plasmid (h) - sc-407358-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 CRISPR Activation Plasmid (h2) - sc-407358-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 Lentiviral Activation Particles (h) - sc-407358-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 Lentiviral Activation Particles (h2) - sc-407358-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOC1 siRNA (h) - sc-78325 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOC1 shRNA Plasmid (h) - sc-78325-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOC1 shRNA (h) Lentiviral Particles - sc-78325-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU083411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8699 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8699 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03627 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03627

FILIP1L siRNA (Human) - CRH7718 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FILIP1L - MBS8205436 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FILIP1L (NM_182909.2) - SHH295069 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FILIP1L(NM_001042459.1) - SHH060059 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FILIP1L(NM_014890.2) - SHH060077 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FILIP1L(NM_182909.2) - SHH060095 from Creative biogene

Category siRNA
Species Reactivities Human

Human FILIP1L siRNA - orb268220 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FILIP1L shRNA Plasmid (Human) - CHH7718 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FILIP1L miRNA 3'UTR clone - MiUTR1H-03659 from Creative biogene

Species Reactivities Human

FILIP1L miRNA 3'UTR clone - MiUTR1H-03660 from Creative biogene

Species Reactivities Human
Search more