Gene Symbol | SULT1A1 |
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Entrez Gene | 6817 |
Alt Symbol | HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 |
Species | Human |
Gene Type | protein-coding |
Description | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
Other Description | P-PST 1|aryl sulfotransferase 1|phenol-sulfating phenol sulfotransferase 1|sulfotransferase 1A1|thermostable phenol sulfotransferase1|ts-PST |
Swissprots | Q9UGG7 Q9BVU6 Q2NL71 Q92818 P50225 Q86U58 |
Accessions | AAA60595 AAB09597 AAB09759 AAC50480 AAC51816 P50225 AB062428 BAB93491 AB209149 BAD92386 AJ007418 CAA07495 AL558375 BC000923 AAH00923 BC110887 AAI10888 BG482944 BG990719 BI459867 BI460081 BM927749 BM984308 BT007324 AAP35988 CV023878 DQ890995 ABM81921 DQ894172 ABM85098 L10819 AAA35562 L19955 AAA02935 L19999 AAA99892 U09031 AAA18613 U26309 AAA67895 X78283 CAA55089 X84654 CAA59147 NM_001055 NP_001046 NM_177529 NP_803565 NM_177530 NP_803566 NM_177534 NP_803878 NM_177536 NP_803880 |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N- hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. {ECO:0000269|PubMed:12471039, ECO:0000269|PubMed:16221673}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Liver, lung, adrenal, brain, platelets and skin. |
Top Pathways | Chemical carcinogenesis |
SULT1 (C-16) - sc-27980 from Santa Cruz Biotechnology
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SULT1 (3F10) - sc-59705 from Santa Cruz Biotechnology
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SULT1A1 (Z-21) - sc-130883 from Santa Cruz Biotechnology
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Anti-SULT1A1 antibody - ab38411 from Abcam
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Anti-SULT1A1 antibody - ab57849 from Abcam
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Anti-SULT1A1 antibody [8B8] - ab124036 from Abcam
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Anti-SULT1A1 antibody [9B7] - ab124011 from Abcam
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, AP) - LS-C246035 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, APC) - LS-C246036 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, FITC) - LS-C246038 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, Biotin) - LS-C246039 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, PE) - LS-C246040 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal, Azide-free, HRP) - LS-C247903 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa2-295, Biotin) - LS-C298438 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa3-291, Biotin) - LS-C301286 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa3-291, FITC) - LS-C304621 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody - LS-C192910 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa2-295, FITC) - LS-C305288 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal) - LS-C328797 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa2-295) - LS-C295884 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa3-291) - LS-C295885 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (clone 1F8) - LS-C198285 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (Internal) - LS-C98543 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody (aa3-285) - LS-C314736 from LifeSpan Bioscience
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Anti-Sulfotransferase 1A1 / SULT1A1 Antibody - LS-C331573 from LifeSpan Bioscience
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