Gene Symbol | SULT1A1 |
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Entrez Gene | 6817 |
Alt Symbol | HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 |
Species | Human |
Gene Type | protein-coding |
Description | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
Other Description | P-PST 1|aryl sulfotransferase 1|phenol-sulfating phenol sulfotransferase 1|sulfotransferase 1A1|thermostable phenol sulfotransferase1|ts-PST |
Swissprots | Q9UGG7 Q9BVU6 Q2NL71 Q92818 P50225 Q86U58 |
Accessions | AAA60595 AAB09597 AAB09759 AAC50480 AAC51816 P50225 AB062428 BAB93491 AB209149 BAD92386 AJ007418 CAA07495 AL558375 BC000923 AAH00923 BC110887 AAI10888 BG482944 BG990719 BI459867 BI460081 BM927749 BM984308 BT007324 AAP35988 CV023878 DQ890995 ABM81921 DQ894172 ABM85098 L10819 AAA35562 L19955 AAA02935 L19999 AAA99892 U09031 AAA18613 U26309 AAA67895 X78283 CAA55089 X84654 CAA59147 NM_001055 NP_001046 NM_177529 NP_803565 NM_177530 NP_803566 NM_177534 NP_803878 NM_177536 NP_803880 |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N- hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. {ECO:0000269|PubMed:12471039, ECO:0000269|PubMed:16221673}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Liver, lung, adrenal, brain, platelets and skin. |
Top Pathways | Chemical carcinogenesis |
SULT1A1 CRISPR/Cas9 KO Plasmid (h) - sc-417793 from Santa Cruz Biotechnology
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SULT1A1 HDR Plasmid (h) - sc-417793-HDR from Santa Cruz Biotechnology
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SULT1A1 Double Nickase Plasmid (h) - sc-417793-NIC from Santa Cruz Biotechnology
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SULT1A1 Double Nickase Plasmid (h2) - sc-417793-NIC-2 from Santa Cruz Biotechnology
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SULT1A1 CRISPR Activation Plasmid (h) - sc-417793-ACT from Santa Cruz Biotechnology
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SULT1A1 CRISPR Activation Plasmid (h2) - sc-417793-ACT-2 from Santa Cruz Biotechnology
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SULT1A1 Lentiviral Activation Particles (h) - sc-417793-LAC from Santa Cruz Biotechnology
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SULT1A1 Lentiviral Activation Particles (h2) - sc-417793-LAC-2 from Santa Cruz Biotechnology
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SULT1A1 siRNA (h) - sc-106578 from Santa Cruz Biotechnology
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SULT1A1 shRNA Plasmid (h) - sc-106578-SH from Santa Cruz Biotechnology
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SULT1A1 shRNA (h) Lentiviral Particles - sc-106578-V from Santa Cruz Biotechnology
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Cytosolic Sulfotransferase 1A1/SULT1A1 RNAi - H00006817-R02 from Novus Biologicals
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Cytosolic Sulfotransferase 1A1/SULT1A1 RNAi - H00006817-R01 from Novus Biologicals
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Cytosolic Sulfotransferase 1A1/SULT1A1 RNAi - H00006817-R05 from Novus Biologicals
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Cytosolic Sulfotransferase 1A1/SULT1A1 RNAi - H00006817-R03 from Novus Biologicals
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Cytosolic Sulfotransferase 1A1/SULT1A1 RNAi - H00006817-R04 from Novus Biologicals
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MISSION® esiRNA - EHU107551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20815 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20815 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01464 from Sigma-Aldrich
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SULT1A1 siRNA (Human) - CRH4661 from Cohesion Biosciences
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SULT1A1 - MBS8222252 from MyBioSource
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shRNA set against Human SULT1A1 (NM_001055.3) - SHH420696 from Creative biogene
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Human SULT1A1 siRNA - orb265163 from Biorbyt
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SULT1A1 shRNA Plasmid (Human) - CHH4661 from Cohesion Biosciences
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