Gene Symbol | SCUBE1 |
---|---|
Entrez Gene | 80274 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | signal peptide, CUB domain, EGF-like 1 |
Other Description | signal peptide, CUB and EGF-like domain-containing protein 1|signal peptide-CUB domain-EGF-related 1 |
Swissprots | Q5R336 Q8IWY4 |
Accessions | EAW73295 EAW73296 EAW73297 EAW73298 EAW73299 EAW73300 EAW73301 EAW73302 Q8IWY4 AF525689 AAN77133 AK127719 BAC87098 BC047916 AAH47916 BC127263 AAI27264 BC156731 AAI56732 BG901065 BM714681 BQ183912 BU101852 BX280767 DN991996 DR003420 XM_005261752 XP_005261809 XM_011530389 XP_011528691 XM_011530390 XP_011528692 XM_011530391 XP_011528693 NM_173050 NP_766638 |
Function | Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology. {ECO:0000269|PubMed:16753137}. |
Subcellular Location | Secreted. Cell membrane; Peripheral membrane protein. |
Tissue Specificity | Detected in endothelial cells. Highly expressed in platelets. Stored in platelet alpha granules, and transferred to the cell surface upon activation and aggregation. A smaller form, probably produced by limited proteolysis, after being released from the storage granules, is associated with thrombus and localized with the subendothelial matrices in atherosclerotic plaques. {ECO:0000269|PubMed:12270931, ECO:0000269|PubMed:16753137}. |
SCUBE1 CRISPR/Cas9 KO Plasmid (h) - sc-413375 from Santa Cruz Biotechnology
|
||||||||
SCUBE1 HDR Plasmid (h) - sc-413375-HDR from Santa Cruz Biotechnology
|
||||||||
SCUBE1 Double Nickase Plasmid (h) - sc-413375-NIC from Santa Cruz Biotechnology
|
||||||||
SCUBE1 Double Nickase Plasmid (h2) - sc-413375-NIC-2 from Santa Cruz Biotechnology
|
||||||||
SCUBE1 CRISPR Activation Plasmid (h) - sc-413375-ACT from Santa Cruz Biotechnology
|
||||||||
SCUBE1 CRISPR Activation Plasmid (h2) - sc-413375-ACT-2 from Santa Cruz Biotechnology
|
||||||||
SCUBE1 Lentiviral Activation Particles (h) - sc-413375-LAC from Santa Cruz Biotechnology
|
||||||||
SCUBE1 Lentiviral Activation Particles (h2) - sc-413375-LAC-2 from Santa Cruz Biotechnology
|
||||||||
SCUBE1 siRNA (h) - sc-76461 from Santa Cruz Biotechnology
|
||||||||
SCUBE1 shRNA Plasmid (h) - sc-76461-SH from Santa Cruz Biotechnology
|
||||||||
SCUBE1 shRNA (h) Lentiviral Particles - sc-76461-V from Santa Cruz Biotechnology
|
||||||||
SCUBE1 RNAi - H00080274-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU146411 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN18975 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18975 from Sigma-Aldrich
|
||||||||
SCUBE1 siRNA (Human) - CRJ2835 from Cohesion Biosciences
|
||||||||
SCUBE1 - MBS8235985 from MyBioSource
|
||||||||
shRNA set against Human SCUBE1 (NM_173050.3) - SHH403136 from Creative biogene
|
||||||||
Human SCUBE1 siRNA - orb273336 from Biorbyt
|
||||||||
SCUBE1 shRNA Plasmid (Human) - CHJ2835 from Cohesion Biosciences
|
||||||||
SCUBE1 miRNA 3'UTR clone - MiUTR3H-12078 from Creative biogene
|