TDRD6

Gene Symbol TDRD6
Entrez Gene 221400
Alt Symbol CT41.2, NY-CO-45, SPATA36, TDR2, bA446F17.4
Species Human
Gene Type protein-coding
Description tudor domain containing 6
Other Description antigen NY-CO-45|cancer/testis antigen 41.2|spermatogenesis associated 36|tudor domain-containing protein 6|tudor repeat 2
Swissprots Q6ZMX5 O60522 F5H5M3 Q5VTS4 B3KWU2 Q5HYB1
Accessions EAX04300 O60522 AF039442 AAC18034 AK125838 BAG54254 AK131455 BC172752 AAI72752 BX648686 CAI45997 CR936792 EF185284 ABM69146 NM_001010870 NP_001010870 NM_001168359 NP_001161831
Function Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression. {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Note=Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids. Colocalizes in CB with DDX4, PIWIL1, PIWIL2, TDRD1 and TDRD7 (By similarity). {ECO:0000250}.

TDRD6 (D-12) - sc-169546 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TDRD6 antibody - ab88570 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TDRD6 antibody (ab88570) at 1 µg/ml + Testis (Human) Tissue Lysate - adult normal tissue (ab30257) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

TDRD6 Antibody - 38150002 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TDRD6 antibody produced in rabbit - HPA035710 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TDRD6: <B>Cat. No. HPA035710</B>: Immunohistochemical staining of human rectum shows strong nuclear positivity in glandular cells.

Anti-TDRD6 Antibody - ABE231 from EMD Millipore

Prices $287.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TDRD6 antibody - TA590765 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELISA: TDRD6 Antibody

Anti-TDRD6 Antibody - ABE231 from Sigma-Aldrich

Prices $279.00
Sizes abe231
Clonality Polyclonal
Western Blotting Analysis: <br />Representative lot data.  <br />Mouse testis tissue lysate  was probed with Cat. No. ABE231, Anti-TDRD6 (0.5 µg/mL). <br />Proteins were visualized using a Donkey Anti-Rabbit IgG secondary antibody conjugated to HRP and a chemiluminesence detection system. <br />Arrow indicates TDRD6 (~236 /265 kDa). Note:   Uncharacterized bands may be observed at ~28 kDa and ~75 kDa in some lysates.  The full length 250 kDa TDRD6 is proteolyzed by an unknown protease to form a 230 kDa protein after meiosis I.

Recombinant Anti-Human TDRD6 Antibody - MOB-3564z from Creative Biolabs

Host Mouse

Anti-TDRD6 (aa 1700-1800) polyclonal antibody - CABT-BL3552 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal
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