Gene Symbol | TDRD6 |
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Entrez Gene | 221400 |
Alt Symbol | CT41.2, NY-CO-45, SPATA36, TDR2, bA446F17.4 |
Species | Human |
Gene Type | protein-coding |
Description | tudor domain containing 6 |
Other Description | antigen NY-CO-45|cancer/testis antigen 41.2|spermatogenesis associated 36|tudor domain-containing protein 6|tudor repeat 2 |
Swissprots | Q6ZMX5 O60522 F5H5M3 Q5VTS4 B3KWU2 Q5HYB1 |
Accessions | EAX04300 O60522 AF039442 AAC18034 AK125838 BAG54254 AK131455 BC172752 AAI72752 BX648686 CAI45997 CR936792 EF185284 ABM69146 NM_001010870 NP_001010870 NM_001168359 NP_001161831 |
Function | Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Note=Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids. Colocalizes in CB with DDX4, PIWIL1, PIWIL2, TDRD1 and TDRD7 (By similarity). {ECO:0000250}. |
TDRD6 CRISPR/Cas9 KO Plasmid (h) - sc-415127 from Santa Cruz Biotechnology
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TDRD6 HDR Plasmid (h) - sc-415127-HDR from Santa Cruz Biotechnology
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TDRD6 Double Nickase Plasmid (h) - sc-415127-NIC from Santa Cruz Biotechnology
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TDRD6 Double Nickase Plasmid (h2) - sc-415127-NIC-2 from Santa Cruz Biotechnology
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TDRD6 CRISPR Activation Plasmid (h) - sc-415127-ACT from Santa Cruz Biotechnology
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TDRD6 CRISPR Activation Plasmid (h2) - sc-415127-ACT-2 from Santa Cruz Biotechnology
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TDRD6 Lentiviral Activation Particles (h) - sc-415127-LAC from Santa Cruz Biotechnology
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TDRD6 Lentiviral Activation Particles (h2) - sc-415127-LAC-2 from Santa Cruz Biotechnology
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TDRD6 siRNA (h) - sc-95484 from Santa Cruz Biotechnology
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TDRD6 shRNA Plasmid (h) - sc-95484-SH from Santa Cruz Biotechnology
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TDRD6 shRNA (h) Lentiviral Particles - sc-95484-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU012101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21190 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21190 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04261 from Sigma-Aldrich
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TDRD6 siRNA (Human) - CRJ6511 from Cohesion Biosciences
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TDRD6 RNAi - H00221400-R01 from Novus Biologicals
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TDRD6 - MBS8237550 from MyBioSource
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shRNA set against Human TDRD6 (NM_001010870.2) - SHH425376 from Creative biogene
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Human TDRD6 siRNA - orb277012 from Biorbyt
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TDRD6 shRNA Plasmid (Human) - CHJ6511 from Cohesion Biosciences
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