| Gene Symbol |
CYP39A1
|
| Entrez Gene |
51302
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 39, subfamily A, polypeptide 1
|
| Other Description |
24-hydroxycholesterol 7-alpha-hydroxylase|cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1
|
| Swissprots |
Q96FW5 Q5VTT0 Q9NYL5
|
| Accessions |
EAX04297 Q9NYL5 AF237982 AAF63329 AK292263 BAF84952 AK301604 BAH13522 AK307986 BC010358 AAH10358 BC012548 BC034323 BG199773 DC336695 DQ892889 ABM83815 EU176719 ABW03520 XM_005249171 XP_005249228 XM_011514655 XP_011512957 XM_011514656 XP_011512958 XM_011514657 XP_011512959 XM_011514658 XP_011512960 NM_001278738 NP_001265667 NM_001278739 NP_001265668 NM_016593 NP_057677
|
| Function |
Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha- hydroxylated product.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Liver specific.
|
| Top Pathways |
Primary bile acid biosynthesis
|
![Western Blot: CYP39A1 Overexpression Lysate (Adult Normal) [NBP2-07001] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CYP39A1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8985_CYP39A1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07001-img0001.jpg)