Gene Symbol | EEF2 |
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Entrez Gene | 1938 |
Alt Symbol | EEF-2, EF-2, EF2, SCA26 |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation elongation factor 2 |
Other Description | elongation factor 2|polypeptidyl-tRNA translocase |
Swissprots | D6W618 P13639 Q58J86 B2RMP5 |
Accessions | EAW69274 EAW69275 P13639 AK297398 BAG59838 AK298498 BAG60705 AK299225 BAG61260 AU118535 AY942181 AAX34409 BC006547 AAH06547 BC024689 AAH24689 BC126259 AAI26260 BC136313 AAI36314 HQ258667 ADR83418 M19997 AAA50388 X51466 CAA35829 Z11692 CAA77750 NM_001961 NP_001952 |
Function | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. |
Subcellular Location | Cytoplasm. Nucleus {ECO:0000269|PubMed:24648518}. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. {ECO:0000269|PubMed:24648518}. |
Top Pathways | Oxytocin signaling pathway, AMPK signaling pathway |
Human EEF2 peptide - ab33521 from Abcam
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Human EEF2 peptide - ab33522 from Abcam
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Human EEF2 protein fragment - ab183170 from Abcam
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EEF2 / Elongation Factor 2 Antibody Blocking Peptide - LS-E21382 from LifeSpan Bioscience
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Recombinant Human eEF-2 Protein - H00001938-P01 from Novus Biologicals
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EEF2-Antibody-C-term-Blocking-Peptide - BP2906b from Abgent, a WuXi AppTec company
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EEF2-Antibody-N-term-Blocking-Peptide - BP2906a from Abgent, a WuXi AppTec company
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Recombinant human Elongation factor 2 (OPCA00072) - OPCA00072 from Aviva Systems Biology
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Human EEF2 EF2 protein - orb244171 from Biorbyt
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EEF2 Blocking Peptide - 33R-9020 from Fitzgerald
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EEF2 protein (His tag) - 80R-3897 from Fitzgerald
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EEF2 Blocking Peptide - abx062098 from Abbexa
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EEF2 (574-858, His-tag) - AR51584PU-N from Acris Antibodies
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EEF2 (574-858, His-tag) - AR51584PU-S from Acris Antibodies
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EEF2 - H00001938-P01-10 from Acris Antibodies
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EEF2 - H00001938-P01-25 from Acris Antibodies
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EEF2 fusion protein - Ag13826 from Proteintech Group
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EEF2 fusion protein - ag13859 from Proteintech Group
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Recombinant Human EEF2, His-tagged - EEF2-28390TH from Creative Biomart
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Recombinant Human EEF2, GST-tagged - EEF2-12294H from Creative Biomart
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Recombinant Human EEF2, GST-tagged - EEF2-382H from Creative Biomart
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Recombinant Human EEF2, MYC/DDK-tagged - EEF2-859H from Creative Biomart
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Recombinant Human EEF2, His-tagged - EEF2-8932H from Creative Biomart
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EEF2 Blocking Peptide - CBP3204 from Cohesion Biosciences
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EEF2 (pT56) Blocking Peptide - CBP3908 from Cohesion Biosciences
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