| Gene Symbol |
KLHL17
|
| Entrez Gene |
339451
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kelch-like family member 17
|
| Other Description |
actinfilin|kelch-like 17|kelch-like protein 17
|
| Swissprots |
Q6TDP4 Q5SV94
|
| Accessions |
EAW56300 EAW56301 EAW56302 EAW56303 Q6TDP4 AA774437 AK127585 BAG54529 AK293258 BAG56790 AY423763 AAR03710 BC033192 BC045768 AAH45768 BC105742 AAI05743 BC166618 AAI66618 CA432461 XM_005244744 XP_005244801 XM_006710600 XP_006710663 XM_006710601 XP_006710664 XR_426604 XR_426605 NM_198317 NP_938073
|
| Function |
Substrate-recognition component of some cullin-RING- based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Postsynaptic density. {ECO:0000250}.
|