Gene Symbol | KLHL17 |
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Entrez Gene | 339451 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | kelch-like family member 17 |
Other Description | actinfilin|kelch-like 17|kelch-like protein 17 |
Swissprots | Q6TDP4 Q5SV94 |
Accessions | EAW56300 EAW56301 EAW56302 EAW56303 Q6TDP4 AA774437 AK127585 BAG54529 AK293258 BAG56790 AY423763 AAR03710 BC033192 BC045768 AAH45768 BC105742 AAI05743 BC166618 AAI66618 CA432461 XM_005244744 XP_005244801 XM_006710600 XP_006710663 XM_006710601 XP_006710664 XR_426604 XR_426605 NM_198317 NP_938073 |
Function | Substrate-recognition component of some cullin-RING- based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Postsynaptic density. {ECO:0000250}. |
KLHL17 CRISPR/Cas9 KO Plasmid (h) - sc-409094 from Santa Cruz Biotechnology
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KLHL17 HDR Plasmid (h) - sc-409094-HDR from Santa Cruz Biotechnology
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KLHL17 Double Nickase Plasmid (h) - sc-409094-NIC from Santa Cruz Biotechnology
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KLHL17 Double Nickase Plasmid (h2) - sc-409094-NIC-2 from Santa Cruz Biotechnology
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KLHL17 CRISPR Activation Plasmid (h) - sc-409094-ACT from Santa Cruz Biotechnology
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KLHL17 CRISPR Activation Plasmid (h2) - sc-409094-ACT-2 from Santa Cruz Biotechnology
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KLHL17 Lentiviral Activation Particles (h) - sc-409094-LAC from Santa Cruz Biotechnology
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KLHL17 Lentiviral Activation Particles (h2) - sc-409094-LAC-2 from Santa Cruz Biotechnology
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KLHL17 siRNA (h) - sc-88478 from Santa Cruz Biotechnology
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KLHL17 shRNA Plasmid (h) - sc-88478-SH from Santa Cruz Biotechnology
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KLHL17 shRNA (h) Lentiviral Particles - sc-88478-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU130971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11276 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11276 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05439 from Sigma-Aldrich
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KLHL17 siRNA (Human) - CRJ7293 from Cohesion Biosciences
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shRNA set against Human KLHL17 (NM_198317.2) - SHH326111 from Creative biogene
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Human KLHL17 siRNA - orb277794 from Biorbyt
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KLHL17 shRNA Plasmid (Human) - CHJ7293 from Cohesion Biosciences
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KLHL17 miRNA 3'UTR clone - MiUTR3H-15179 from Creative biogene
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