| Gene Symbol |
RXRG
|
| Entrez Gene |
6258
|
| Alt Symbol |
NR2B3, RXRC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
retinoid X receptor, gamma
|
| Other Description |
nuclear receptor subfamily 2 group B member 3|retinoic acid receptor RXR-gamma
|
| Swissprots |
P48443 Q6IBU7 A6NIP1
|
| Accessions |
EAW90745 P48443 AB307706 BAH02297 AB593015 BAJ83970 AB593016 BAJ83971 AK125497 AK312922 BAG35767 AL538345 BC012063 AAH12063 BE349162 BI768747 BM684530 BM728015 BX118484 CR456705 CAG32986 DA251671 DA893476 EU831976 ACE87417 EU832069 ACE86731 HQ692845 ADZ17356 U38480 AAA80681 NM_001256570 NP_001243499 NM_001256571 NP_001243500 NM_006917 NP_008848 NR_033824
|
| Function |
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}.
|
| Top Pathways |
Small cell lung cancer, Non-small cell lung cancer, Adipocytokine signaling pathway, PPAR signaling pathway, Thyroid cancer
|
![Western Blot: Retinoid X Receptor gamma Overexpression Lysate (Adult Normal) [NBL1-15643] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Retinoid X Receptor gamma.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6999_Retinoid%2520X%2520Receptor%2520gamma%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15643-img0002.jpg)