| Gene Symbol |
WNT8B
|
| Entrez Gene |
7479
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 8B
|
| Other Description |
protein Wnt-8b
|
| Swissprots |
Q8WYK9 Q5VX55 O00771 Q93098
|
| Accessions |
CAA71994 CAI38651 EAW49825 Q93098 AB073637 BAB83924 BC156632 AAI56633 CN276452 X91940 CAA63017 Y11094 CAA71968 NM_003393 NP_003384
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. {ECO:0000269|PubMed:9536085}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Expression is restricted to the brain, and more specifically to the forebrain. {ECO:0000269|PubMed:9536085}.
|
| Top Pathways |
Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection
|
![Western Blot: Wnt8b Overexpression Lysate (Adult Normal) [NBL1-17879] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Wnt8b.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10045_Wnt8b%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17879-img0002.jpg)